Compare carbidopa / levodopa / entacapone vs. carbidopa / levodopa extended release
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Stalevo (carbidopa / levodopa / entacapone) is a good choice for Parkinson's disease, especially when carbidopa/levodopa starts losing its effect.
Treats Parkinson's disease.
Sinemet CR (carbidopa / levodopa extended release) is the first choice treatment for Parkinson's disease.
Upsides
- It combines three medicines into one pill so you don't have to take so many pills daily.
- Stalevo (carbidopa / levodopa / entacapone) is available as a generic.
- Sinemet CR (carbidopa / levodopa extended release) is released over a long period of time in your body and can allow you to take fewer pills less frequently.
Downsides
- You would first start by taking Stalevo (carbidopa / levodopa / entacapone) as two different pills, carbidopa/levodopa and entacapone, before you get switched over to Stalevo (carbidopa / levodopa / entacapone).
- It's less customizable since there are only a few fixed combinations available.
- Sinemet CR (carbidopa / levodopa extended release) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
- Your saliva, sweat and urine may have dark color and stain your clothing while taking Sinemet CR (carbidopa / levodopa extended release).
- Sinemet CR (carbidopa / levodopa extended release) will lose its effect over time. If you notice it wearing off sooner than you'd like, talk to your doctor.
- Sinemet CR (carbidopa / levodopa extended release) may cause unusual cravings in some people.
Used for
Dosage forms
- Pill
- Extended release
Price
Lowest price
$150.06
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$23.33
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Side effects
20possible side effects
- Difficulty controlling movements25%
- Muscle spasm10%
- Changes in urine color10%
- Discolored urine10%
- Muscle rigidity9%
- Dizziness8%
- Abdominal pain8%
- Fatigue6%
- Constipation6%
- Back pain5%
- Vomiting4%
- Dry mouth3%
- Shortness of breath3%
- Bruising3%
- Increased sweating2%
- Anxiety2%
- Sleepiness2%
- Indigestion2%
- Flatulence2%
- Weakness2%
15possible side effects
- Difficulty controlling movements17%
- Nausea6%
- Hallucinations4%
- Confusion4%
- Dizziness3%
- Depression2%
- Urinary tract infection2%
- Headache2%
- Unusual dreams2%
- Muscle spasms2%
- Vomiting2%
- Upper respiratory infection2%
- Shortness of breath2%
- Periods of immobility2%
- Back pain2%
Risks and risk factors
- Difficulty controlling movements
- Diarrhea
- Muscle damage
- Changes in blood pressure and falls
- Stomach bleeding
- History of stomach ulcers
- Falling asleep during the day
- Taking other medicines for Parkinson's
- High fever and confusion
- Stopping Sinemet CR (carbidopa / levodopa extended release) suddenly
- Changes in behavior
- Lack of impulse control
- Taking other medicines for Parkinson's disease
- Changes in blood pressure and falls