Compare carbidopa / levodopa / entacapone vs. Duopa
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Stalevo (carbidopa / levodopa / entacapone) is a good choice for Parkinson's disease, especially when carbidopa/levodopa starts losing its effect.
Treats advanced stages of Parkinson's disease.
Duopa (carbidopa / levodopa) pumps carbidopa/levodopa into your body throughout the day. It is reserved for advanced Parkinson's disease when your symptoms become more frequent than the dosing of your tablets.
Upsides
- It combines three medicines into one pill so you don't have to take so many pills daily.
- Stalevo (carbidopa / levodopa / entacapone) is available as a generic.
- Duopa (carbidopa / levodopa) allows you to have better control of your symptoms than oral tablets, especially in later stages of Parkinson's disease.
Downsides
- You would first start by taking Stalevo (carbidopa / levodopa / entacapone) as two different pills, carbidopa/levodopa and entacapone, before you get switched over to Stalevo (carbidopa / levodopa / entacapone).
- It's less customizable since there are only a few fixed combinations available.
- Given via pump so you'll need to have a procedure to attach the pump to your body.
- You'll need to take good care of the pump so that it doesn't get disconnected or infected.
- Duopa (carbidopa / levodopa) only lasts for 16 hours. You may need to take an extra dose of carbidopa/levodopa as tablet for nighttime control.
- You need to keep Duopa (carbidopa / levodopa) in a fridge, but it should sit at room temperature 20 minutes before infusion.
Used for
Dosage forms
- Pill
- Liquid
Price
Lowest price
$101.59
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$9.00
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Side effects
20possible side effects
- Difficulty controlling movements25%
- Muscle spasm10%
- Changes in urine color10%
- Discolored urine10%
- Muscle rigidity9%
- Dizziness8%
- Abdominal pain8%
- Fatigue6%
- Constipation6%
- Back pain5%
- Vomiting4%
- Dry mouth3%
- Shortness of breath3%
- Bruising3%
- Increased sweating2%
- Anxiety2%
- Sleepiness2%
- Indigestion2%
- Flatulence2%
- Weakness2%
26possible side effects
- Problems with J-tube56%
- Nausea30%
- Constipation22%
- Redness and swelling at the J-tube site19%
- Difficulty controlling movements14%
- Depression11%
- Discharge at the J-tube site11%
- Swelling in the arms and legs8%
- High blood pressure8%
- Flu and cold8%
- Sore throat8%
- Collapsed lung8%
- Confusion8%
- Anxiety8%
- Dizziness8%
- Hiatal hernia8%
- Intestinal blockage5%
- Sleep problems5%
- Fever5%
- Scar tissue5%
- Rash5%
- Urinary tract infection5%
- Hallucinations5%
- Psychotic disorder5%
- Diarrhea5%
- Indigestion5%
Risks and risk factors
- Difficulty controlling movements
- Diarrhea
- Muscle damage
- Changes in blood pressure and falls
- Stomach bleeding
- History of stomach ulcers
- Stomach problems
- Surgery to place the J-tube
- Falling asleep during the day
- Taking other medicines for Parkinson's
- High fever and confusion
- Stopping Duopa (carbidopa / levodopa) suddenly
- Changes in behavior
- Lack of impulse control
- Taking other medicines for Parkinson's disease