Compare Casodex vs. Xtandi

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Helps treat metastatic prostate cancer.

Casodex (bicalutamide) treats later stages of prostate cancer in combination with another medication, but it can cause hot flashes.

No information currently available
Upsides
  • Available in a cheaper, generic version.
  • The pill can be adminstered at home instead of injected at an infusion clinic.
  • Safe for use even if you have kidney disease.
  • Less side-effects than other medicines that work similarly.
No information currently available
Downsides
  • Casodex (bicalutamide) doesn't control cancer as well as newer medicines that work similarly.
  • Casodex (bicalutamide) damages the lungs and liver so not a good option if you have pre-existing lung or liver disease.
No information currently available
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Used for
  • Metastatic prostate cancer
  • Castration-resistant
  • In patients who have previously received docetaxel
  • -
Dosage forms
  • Pill
  • Pill
Price
No pricing information available
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Reviews
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Side effects
52possible side effects
  • Hot flashes
    53%
  • General pain
    35%
  • Back pain
    25%
  • Weakness
    22%
  • Constipation
    22%
  • Pelvic pain
    21%
  • Infection
    18%
  • Nausea
    15%
  • Swelling in the limbs
    13%
  • Labored breathing
    13%
  • Diarrhea
    12%
  • Excessive urination at night
    12%
  • Blood in urine
    12%
  • Stomach pain
    11%
  • Anemia
    11%
  • Dizziness
    10%
  • Bone pain
    9%
  • Rash
    9%
  • Urinary Tract Infection
    9%
  • Male breasts
    9%
  • Chest pain
    8%
  • High blood pressure
    8%
  • Burning/tingling sensation
    8%
  • Increased cough
    8%
  • Inflammation of back of throat
    8%
  • Headache
    7%
  • Flu syndrome
    7%
  • Increase liver enzyme test
    7%
  • Indigestion
    7%
  • Weight loss
    7%
  • Muscle weakness
    7%
  • Difficulty sleeping
    7%
  • Impotence
    7%
  • Gas
    6%
  • Loss of appetite
    6%
  • Vomiting
    6%
  • High blood sugar
    6%
  • Inflammation of bronchial tubes
    6%
  • Sweating
    6%
  • Breast pain
    6%
  • Urinary frequency
    6%
  • Increase alkaline phosphatase
    5%
  • Weight gain
    5%
  • Joint inflammation
    5%
  • Anxiety
    5%
  • Urinary retention
    5%
  • Impaired urination
    5%
  • Fracture
    4%
  • Depression
    4%
  • Pneumonia
    4%
  • Stuffy nose
    4%
  • Urinary incontinence
    4%
See more detailed side effects
The Xtandi (Enzalutamide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver disease
  • Development of breasts and breast pain
  • Changes in fertility
See more detailed risks and warnings
No information currently available