Compare Celebrex vs. Allopurinol
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves pain and inflammation.
Celebrex (celecoxib) works well for treating pain, but is not a good option if you have heart problems.
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3.4/ 5 average rating with 550 reviewsforCelebrex
Lowers uric acid levels in blood, and prevents gout flare-ups.
Zyloprim (allopurinol) works well to prevent gout attacks and is cheaper than some alternatives, but it takes a few weeks to start working.
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3.7/ 5 average rating with 21 reviewsforAllopurinol
Upsides
- Celebrex (celecoxib) effectively relieves pain and inflammation for many types of pain conditions including osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, and menstrual cramps.
- Celebrex (celecoxib) causes less stomach problems compared to other NSAIDs like ibuprofen or naproxen.
- Celebrex (celecoxib) is available as a cheaper, generic form.
- Celebrex (celecoxib) has the lowest risk of heart attack compared to other NSAIDs.
- Zyloprim (allopurinol) works well to lower uric acid in the body.
- It is available as a generic medication.
Downsides
- The longer you take Celebrex (celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding.
- Celebrex (celecoxib) can affect your kidneys or cause permanent kidney damage if taken for a long time.
- Celebrex (celecoxib) shouldn't be used if you have an allergy to sulfa medications.
- Zyloprim (allopurinol) can raise the number of gout attacks in the first few weeks.
- It can take 2 to 6 weeks to feel the full effects of Zyloprim (allopurinol).
- Kidney stones can form while taking Zyloprim (allopurinol), so you need to drink a lot of fluids to help prevent this.
Used for
- Gout
- High uric acid in cancer
- Recurrent kidney stones
Dosage forms
- Pill
- Pill
- Injection
Price
Lowest price
$8.23
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$106.47
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Reviews
550 reviews so far
57%
saidit'sworth it
38%
saiditworked well
14%
saidit'sa big hassle
Have you used Celebrex (celecoxib)?
Leave a review21 reviews so far
71%
saidit'sworth it
52%
saiditworked well
5%
saidit'sa big hassle
Have you used Zyloprim (allopurinol)?
Leave a reviewSide effects
16possible side effects
- Headache16%
- Indigestion9%
- Upper respiratory infection8%
- Diarrhea6%
- Sinus infection5%
- Stomach pain4%
- Nausea4%
- Back pain3%
- Injury3%
- Gas2%
- Swelling in the limbs2%
- Dizziness2%
- Difficulty sleeping2%
- Sore throat2%
- Stuffy nose2%
- Rash2%
The Zyloprim (allopurinol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Heart attack and stroke
- Long-term use
- History of heart disease
- History of heart bypass surgery (coronary artery bypass graft/CABG)
- Stomach bleeding
- Age 65 or older
- History of GI bleed or peptic ulcer disease
- Longer duration of treatment
- Use of oral corticosteroids, aspirin, anticoagulants, selective serotonin reuptake inhibitors (SSRIs)
- Smoking
- Alcohol use
- Increased blood pressure
- History of high blood pressure
- Heart failure risk
- Heart failure
- Allergic reaction
- History of sulfa allergy
- Lowered kidney function
- History of kidney problems
- Dehydration
- Heart failure
- Liver problems
- Taking diuretic medications
- ACE inhibitors
- Angiotensin II receptor blockers
- Age 65 or older
- More gout attacks
- Kidney stones
- History of kidney stones
- Skin rash
- Liver disease
- Sleepiness or dizziness
- Taking other medications that also cause sleepiness
- Recreational drug use
- Excessive alcohol use
- Elderly