Compare Celebrex vs. Plavix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Celebrex (celecoxib)

Prescription only

Plavix (clopidogrel)

Prescription only
Relieves pain and inflammation.

Celebrex (celecoxib) works well for treating pain, but is not a good option if you have heart problems.

3.4/ 5 average rating with 550 reviewsforCelebrex
Prevents blood clots.

Plavix (clopidogrel) is a cheap, generically available blood thinner that protects you from clots after you've had a heart attack or surgery.

3.7/ 5 average rating with 343 reviewsforPlavix
Upsides
  • Celebrex (celecoxib) effectively relieves pain and inflammation for many types of pain conditions including osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, and menstrual cramps.
  • Celebrex (celecoxib) causes less stomach problems compared to other NSAIDs like ibuprofen or naproxen.
  • Celebrex (celecoxib) is available as a cheaper, generic form.
  • Celebrex (celecoxib) has the lowest risk of heart attack compared to other NSAIDs.
  • Plavix (clopidogrel) can help lower your risk of getting a stroke or heart attack.
  • You only need to take it once a day.
  • A genetic test is available to determine whether Plavix (clopidogrel) will be an effective treatment option for you.
Downsides
  • The longer you take Celebrex (celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding.
  • Celebrex (celecoxib) can affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Celebrex (celecoxib) shouldn't be used if you have an allergy to sulfa medications.
  • Raises your risk of bleeding and bruising, which can be serious and life-threatening.
  • May not be safe to be taken with many other medicines or supplements.
  • If you've taken too much Plavix (clopidogrel) and you're bleeding, plasma transfusions are required to stop the bleeding.
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Used for
Dosage forms
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Price
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Reviews
550 reviews so far
57%
saidit'sworth it
38%
saiditworked well
14%
saidit'sa big hassle

Have you used Celebrex (celecoxib)?

Leave a review
343 reviews so far
59%
saidit'sworth it
49%
saiditworked well
16%
saidit'sa big hassle

Have you used Plavix (clopidogrel)?

Leave a review
Side effects
16possible side effects
  • Headache
    16%
  • Indigestion
    9%
  • Upper respiratory infection
    8%
  • Diarrhea
    6%
  • Sinus infection
    5%
  • Stomach pain
    4%
  • Nausea
    4%
  • Back pain
    3%
  • Injury
    3%
  • Gas
    2%
  • Swelling in the limbs
    2%
  • Dizziness
    2%
  • Difficulty sleeping
    2%
  • Sore throat
    2%
  • Stuffy nose
    2%
  • Rash
    2%
See more detailed side effects
The Plavix (clopidogrel) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart attack and stroke
    • Long-term use
    • History of heart disease
    • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Stomach bleeding
    • Age 65 or older
    • History of GI bleed or peptic ulcer disease
    • Longer duration of treatment
    • Use of oral corticosteroids, aspirin, anticoagulants, selective serotonin reuptake inhibitors (SSRIs)
    • Smoking
    • Alcohol use
  • Increased blood pressure
    • History of high blood pressure
  • Heart failure risk
    • Heart failure
  • Allergic reaction
    • History of sulfa allergy
  • Lowered kidney function
    • History of kidney problems
    • Dehydration
    • Heart failure
    • Liver problems
    • Taking diuretic medications
    • ACE inhibitors
    • Angiotensin II receptor blockers
    • Age 65 or older
See more detailed risks and warnings
  • Weakened ability to prevent blood clots
    • Taking Prilosec or Nexium
    • People with certain genes that make Plavix (clopidogrel) less effective
  • Life-threatening bleeding
    • History of stomach bleeding
    • Taking other medicines that increase the levels of Plavix (clopidogrel) in your body
    • Taking other blood thinners or medicines that increase the risk of bleeding
  • Unexplained bruising and purple spots on skin
See more detailed risks and warnings