Compare Celebrex vs. prednisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Celebrex (celecoxib)

Prescription only

Deltasone (prednisone)

Prescription only
Relieves pain and inflammation.

Celebrex (celecoxib) works well for treating pain, but is not a good option if you have heart problems.

3.4/ 5 average rating with 550 reviewsforCelebrex
Calms down your immune system.

Deltasone (prednisone) is effective for controlling allergic reactions and conditions involving an overactive immune system. It can quickly make you feel better, but Deltasone (prednisone) can cause serious complications and side effects if taken for a long time.

3.5/ 5 average rating with 540 reviewsforprednisone
Upsides
  • Celebrex (celecoxib) effectively relieves pain and inflammation for many types of pain conditions including osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, and menstrual cramps.
  • Celebrex (celecoxib) causes less stomach problems compared to other NSAIDs like ibuprofen or naproxen.
  • Celebrex (celecoxib) is available as a cheaper, generic form.
  • Celebrex (celecoxib) has the lowest risk of heart attack compared to other NSAIDs.
  • Deltasone (prednisone) effectively treats a variety of conditions involving the immune system.
  • Can help improve energy and stimulate your appetite.
  • Works quickly to provide relief for swelling, rash, asthma attacks, and pain.
  • Good long-term treatment option for autoimmune disorders.
  • Deltasone (prednisone) is available in a generic form.
Downsides
  • The longer you take Celebrex (celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding.
  • Celebrex (celecoxib) can affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Celebrex (celecoxib) shouldn't be used if you have an allergy to sulfa medications.
  • Deltasone (prednisone) can cause unwanted side effects such as mood changes, trouble sleeping, and increase in blood pressure as well as blood sugar at higher doses.
  • Long-term use can cause problems to your skin, bones, eyes, and place you at a higher risk for infections.
  • If Deltasone (prednisone) is used for more than 2 weeks, you will need to work with a doctor to taper off the medicine by gradually decreasing the dose.
  • Deltasone (prednisone) can harm an unborn baby, so it's not a good option for pregnant women.
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Used for
Dosage forms
  • Pill
  • Pill
  • Delayed release pill
  • Liquid
Price
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Reviews
550 reviews so far
57%
saidit'sworth it
38%
saiditworked well
14%
saidit'sa big hassle

Have you used Celebrex (celecoxib)?

Leave a review
540 reviews so far
59%
saidit'sworth it
45%
saiditworked well
20%
saidit'sa big hassle

Have you used Deltasone (prednisone)?

Leave a review
Side effects
16possible side effects
  • Headache
    16%
  • Indigestion
    9%
  • Upper respiratory infection
    8%
  • Diarrhea
    6%
  • Sinus infection
    5%
  • Stomach pain
    4%
  • Nausea
    4%
  • Back pain
    3%
  • Injury
    3%
  • Gas
    2%
  • Swelling in the limbs
    2%
  • Dizziness
    2%
  • Difficulty sleeping
    2%
  • Sore throat
    2%
  • Stuffy nose
    2%
  • Rash
    2%
See more detailed side effects
The Deltasone (prednisone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart attack and stroke
    • Long-term use
    • History of heart disease
    • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Stomach bleeding
    • Age 65 or older
    • History of GI bleed or peptic ulcer disease
    • Longer duration of treatment
    • Use of oral corticosteroids, aspirin, anticoagulants, selective serotonin reuptake inhibitors (SSRIs)
    • Smoking
    • Alcohol use
  • Increased blood pressure
    • History of high blood pressure
  • Heart failure risk
    • Heart failure
  • Allergic reaction
    • History of sulfa allergy
  • Lowered kidney function
    • History of kidney problems
    • Dehydration
    • Heart failure
    • Liver problems
    • Taking diuretic medications
    • ACE inhibitors
    • Angiotensin II receptor blockers
    • Age 65 or older
See more detailed risks and warnings
  • Physicial Dependence
    • Taking high doses of Deltasone (prednisone) for a long period of time
    • Young children
    • Stress such as trauma, injury, or infection
  • Increased risk for infections
    • Taking other medicines that weaken the immune system
    • Taking Deltasone (prednisone) for a long time
    • Those who are not vaccinated against viral illnesses
    • Coming into contact with people who have viral illness
    • History of bacterial or viral conditions
  • Eye problems
    • Those with cataracts and/or glaucoma
    • History of herpes simplex in the eye
  • Changes in heart and kidney function
    • Those who had a recent heart attack
    • History of heart failure, high blood pressure, and kidney problems
  • Effects on bone
    • Taking Deltasone (prednisone) at high doses and/or for a long period of time
    • Infants and young children
    • Age 60 or older
  • Stomach problems
    • History of stomach bleeding
    • History of stomach ulcers
    • History of Ulcerative Colitis
    • Taking Deltasone (prednisone) with other medicines that can also cause stomach problems
See more detailed risks and warnings