Compare Celexa vs. Wellbutrin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Improves mood.
Celexa (citalopram) is good for treating depression and anxiety. Side effects are less likely to happen compared to other antidepressants; however, it is not the best choice for people with heart or liver problems.
●●●●●
3.7/ 5 average rating with 520 reviewsforCelexa
Improves mood.
Wellbutrin (Bupropion) is good for treating depression and has fewer sexual side effects than other antidepressants, but you need to be okay with avoiding alcohol.
●●●●●
3.4/ 5 average rating with 1164 reviewsforWellbutrin
Upsides
- Effectively relieves depression symptoms.
- This medicine is not as drowsy as other antidepressants.
- Available as a generic, which is cheaper.
- Effective at relieving depression symptoms.
- Causes fewer sexual side effects than other antidepressants. Can actually boost sex drive for some people.
- Can be taken with other antidepressants to counteract their sexual side effects.
- Has some stimulant effects, so it can be energizing.
- Can help with ADHD symptoms.
- Also used to suppress appetite and help you quit smoking.
- Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
- Can cause sexual side effects like decreased sex drive, difficulties with orgasm or ejaculation, and minor weight gain (1 to 5 pounds).
- Celexa (citalopram) may not be a good option if you have heart or liver problems.
- Like most antidepressants, Celexa (citalopram) can increase risk of suicidal thoughts and behavior in people younger than 24 years.
- Wellbutrin (Bupropion) can be stimulating, so it can cause anxiety or insomnia the first few days you're taking it.
- Generally not as good as other antidepressants for people who have anxiety.
- It's less likely to cause weight gain than other antidepressants.
- Has a higher risk of causing seizures, especially if you have a seizure disorder, eating disorder, or if you drink alcohol. So, it's not a good medication if you drink a lot.
- It contains the same ingredient as a medication that helps you to stop smoking, (Zyban), so these two meds can't be used together.
- Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
- The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
- Depression
- Seasonal affective disorder prevention
- Smoking cessation
- Bipolar disorder
- Sexual dysfunction from taking SSRI antidepressant
Dosage forms
- Pill
- Liquid
- Pill
- Extended release
Price
Lowest price
$4.00
Find instant savings near youLowest price
$9.00
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
520 reviews so far
61%
saidit'sworth it
51%
saiditworked well
16%
saidit'sa big hassle
Have you used Celexa (citalopram)?
Leave a review1164 reviews so far
60%
saidit'sworth it
40%
saiditworked well
13%
saidit'sa big hassle
Have you used Wellbutrin (Bupropion)?
Leave a reviewSide effects
25possible side effects
- Nausea21%
- Dry mouth20%
- Drowsiness18%
- Difficulty sleeping15%
- Increased sweating11%
- Tremor8%
- Diarrhea8%
- Abnormal ejaculation6%
- Indigestion5%
- Fatigue5%
- Upper airway infection5%
- Stuffy nose5%
- Vomiting4%
- Anxiety4%
- Anorexia4%
- Abdominal pain3%
- Agitation3%
- Menstrual cramps3%
- Sinus infection3%
- Erection difficulties3%
- Fever2%
- Joint pain2%
- Muscle pain2%
- Decreased sex drive2%
- Yawning2%
29possible side effects
- Agitation32%
- Dry mouth28%
- Constipation26%
- Headache/migraine26%
- Nausea/vomiting23%
- Dizziness22%
- Excessive sweating22%
- Tremor21%
- Sleepiness20%
- Insomnia19%
- Blurred vision15%
- Tachycardia11%
- Confusion8%
- Rash8%
- Hostility6%
- Auditory disturbance5%
- Menstrual complaints5%
- Cardiac arrhythmias5%
- Impaired sleep quality4%
- Sensory disturbance4%
- Appetite increase4%
- Palpitations4%
- Hypertension4%
- Impotence3%
- Anxiety3%
- Decreased libido3%
- Gustatory disturbance3%
- Dyspepsia3%
- Hypotension3%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort
- Bipolar disorder
- History of bipolar disorder
- At risk for bipolar disorder
- Withdrawal
- Stopping Celexa (citalopram) abruptly
- Lower maximum dose in some people
- Higher dose
- History of heart problems
- History of liver problems
- 60 years or older
- Increased bleeding
- Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)
- Sexual side effects
- Suicidal thoughts or behavior
- Age 24 years or younger
- Psychiatric effects for smoking cessation
- History of depression
- History of bipolar disorder
- At risk for bipolar disorder
- Withdrawing from nicotine
- Seizures
- History of seizures
- Alcoholism
- Eating disorder
- Higher dose
- Drug interactions
- Mania
- History of bipolar disorder
- At risk for bipolar disorder
- Increased side effects
- Current kidney problems
- Current liver problems
- Weight loss