Compare chloroquine vs. Mefloquine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Prevents and treats malaria, and also treats a type of bowel infection.

Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people.

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Upsides
  • chloroquine is generally safe to use during pregnancy and for children.
  • You can take chloroquine with or without food.
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Downsides
  • chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before.
  • chloroquine is only effective against malaria from certain areas of the world.
  • chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.
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Used for
  • Malaria
  • Mild to moderate
  • Plasmodium falciparum or P vivax Malaria
  • Plasmodium falciparum or vivax; Prophylaxis
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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Side effects
The chloroquine FDA package insert doesn’t have numbers about how common side effects are.
The Lariam (Mefloquine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart problems
    • Heart problems
  • Muscle weakness
    • Long-term use
  • Low blood counts
    • G6PD (glucose-6-phosphate dehydrogenase) deficiency
  • Eye injury
    • Taking high dose of chloroquine
    • Long-term use
    • Taking tamoxifen
    • Low body weight
    • Kidney problems
  • Liver damage
    • Taking other drugs that affect the liver
    • Alcoholism
    • Liver conditions
  • Hearing damage
    • History of hearing problems
See more detailed risks and warnings
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