Compare chlorpromazine vs. thiothixene
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Stabilizes your mood.
Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.
Treats schizophrenia.
Navane (thiothixene) isn't a first choice for treating schizophrenia because of the side effects, but it is cheaper than other medicines.
Upsides
- Acts fast to slow you down during a psychotic episode.
- Can also be used for nausea or migraines.
- Safe for use in children as young as 6 months.
- Comes in a sugar-coated pill for easy administration.
- Navane (thiothixene) is available in generic.
- Navane (thiothixene) is less likely to make you sleepy.
Downsides
- Has more side effects than other medicines like it.
- Can affect how your other medicines work.
- Makes you more sensitive to the sun.
- Can make you dizzy or lightheaded, especially when injected.
- Cannot be stopped right away.
- Side effects include weight gain and high blood sugar.
- Navane (thiothixene) can cause low blood pressure, which can cause fainting or falls if you’re not careful.
- Smoking tobacco can make Navane (thiothixene) work poorly.
Used for
- Acute intermittent porphyria
- Preoperative anxiety
- Bipolar disorder
- Hiccups
- Nausea and vomiting
- Severe behavioral problems
- Schizophrenia
- Tetanus
Dosage forms
- Pill
- Injection
- Pill
Price
Lowest price
$34.12
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$39.50
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Reviews
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Side effects
The Thorazine (chlorpromazine) FDA package insert doesn’t have numbers about how common side effects are.
The Navane (thiothixene) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Increased risk of death
- People over 65 with dementia and psychosis
- Difficulty controlling movements
- Neuroleptic malignant syndrome
- Taking antipsychotic medications
- Breathing problems
- Asthma
- COPD
- Acute respiratory infections
- Heat stroke and dehydration
- Benign prostatic hypertrophy (BPH)
- Urinary retention
- Decreased movement in the intestines
- Higher risk of death
- People age 65 or older with dementia and psychosis
- Difficulty controlling movements
- Neuroleptic malignant syndrome
- Drowsiness and sleepiness
- Drinking alcohol, or taking opioids, benzodiazepines, or sleeping medicines
- Low blood pressure