Compare Claritin-D vs. Advil Cold And Sinus
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats allergies and clears up nasal congestion.
Claritin-D (loratadine / pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness but it can keep you up at night.
●●●●●
3.6/ 5 average rating with 1527 reviewsforClaritin-D
Relieves sinus pain and congestion.
Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.
●●●●●
3.6/ 5 average rating with 1464 reviewsforAdvil Cold And Sinus
Upsides
- This once-daily, single-pill combination conveniently treats congestion and other allergy symptoms.
- It doesn't cause any daytime drowsiness unlike other antihistamines.
- It doesn't require a prescription from your doctor.
- Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a combination medicine that relieves cold symptoms. It's good to use if you have congestion, sore throat, headache, or fever.
- Ibuprofen (a pain reliever) is more effective than acetaminophen at lowering fever and relieving sinus pain.
- Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
Downsides
- The decongestant (pseudoephedrine) can make you anxious or your heart race. You may not sleep as well at night.
- Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
- It may interfere with how your other medicines work. Talk to your doctor or pharmacist before combining with other medicines.
- If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
- The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
- It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
- Pseudoephedrine, the decongestant in Advil Cold And Sinus (Ibuprofen / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
Used for
Dosage forms
- Extended-release pill
- Pill
No pricing information available
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
1527 reviews so far
69%
saidit'sworth it
39%
saiditworked well
8%
saidit'sa big hassle
Have you used Claritin-D (loratadine / pseudoephedrine)?
Leave a review1464 reviews so far
75%
saidit'sworth it
34%
saiditworked well
6%
saidit'sa big hassle
Have you used Advil Cold And Sinus (Ibuprofen / Pseudoephedrine)?
Leave a reviewSide effects
12possible side effects
- Headache19%
- Insomnia16%
- Dry mouth14%
- Drowin7%
- Nervousness or anxiety5%
- Dizziness4%
- Indigestion3%
- Nausea3%
- Sore throat3%
- Fatigue3%
- Increased thirst2%
- Loss of appetite2%
The Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- High blood pressure
- History of high blood pressure
- Glaucoma
- Restlesness
- History of heart problems
- Overactive thyroid
- Diabetes
- Over age 65
- Difficulty concentrating
- Taking with alcohol
- Taking other medicines that make you less alert
- Stomach bleeding
- History of stomach bleeding or ulcers
- Age 60 years or older
- Taking aspirin, NSAIDs, or blood thinners
- Drinking more than 3 alcoholic beverages a day
- Harm to fetus
- Women of childbearing age
- High blood pressure
- History of high blood pressure
- Lower kidney function
- Kidney disease
- Heart failure
- Liver disease
- Taking high blood pressure medications
- Age 65 years or older
- Heart attack or stroke
- History of heart problems
- Age 65 years or older
- Taking with aspirin