Compare Cleocin vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Topical treatment for acne.

Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.

3.5/ 5 average rating with 115 reviewsforCleocin
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

3.6/ 5 average rating with 473 reviewsforBactrim
Upsides
  • Available in generic.
  • Topical form treats acne.
  • Available in different oral forms: tablet, capsule, and suspension.
  • Available in forms to treat skin infections and vaginal infections.
  • Used to treat many types of bacterial infections.
  • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
  • Can be taken with or without food.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
  • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
  • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
  • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
  • If you're taking the topical form, it can cause sensitivity and irritation.
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
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Used for
Dosage forms
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
  • Pill
  • Liquid
Price
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Reviews
115 reviews so far
57%
saidit'sworth it
43%
saiditworked well
19%
saidit'sa big hassle

Have you used Cleocin T (Clindamycin Phosphate)?

Leave a review
473 reviews so far
59%
saidit'sworth it
49%
saiditworked well
22%
saidit'sa big hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
Side effects
The Cleocin T (Clindamycin Phosphate) FDA package insert doesn’t have numbers about how common side effects are.
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Diarrhea
  • Liver damage
    • History of liver disease
  • Rash
See more detailed risks and warnings
  • Diarrhea
  • Sunburn
  • Rash
  • Harm to fetus
  • Lower kidney function
    • Elderly
    • Taking other medicines that lower kidney function
See more detailed risks and warnings