Compare Climara vs. Femring

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.

Climara (estradiol patch) is a treatment for low estrogen that is used only once weekly, and it may have fewer side effects than oral estrogen pills.

Relieves hot flashes and vaginal dryness due to menopause.

Femring (estradiol acetate vaginal ring) is dosed more conveniently than other forms of estrogen therapy (pills, gels, patches, and creams), but needs to be inserted directly into the vagina.

2.6/ 5 average rating with 31 reviewsforFemring
Upsides
  • Climara (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to or can't take daily pills.
  • Climara (estradiol patch) is available as a generic product, which lowers the cost.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy.
  • Femring (estradiol acetate vaginal ring) may be more convenient since it is dosed once every 3 months compared to other medications that need to taken daily or twice weekly.
  • Many women find Femring (estradiol acetate vaginal ring) more comfortable to use and easier to apply than creams or gels.
  • Unlike other topical therapies, Femring (estradiol acetate vaginal ring) works to improve both hot flashes and vaginal dryness caused by menopause.
Downsides
  • The patch can fall off, especially if you like to regularly swim, take baths or use saunas or steamrooms.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to use the Climara (estradiol patch) with another hormone called progestin to lower your risk of uterine cancer.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, underactive thyroid and migraines.
  • If you're only having vaginal dryness or inflammation and not hot flashes, it's better to use creams that you can apply to the affected area instead of Climara (estradiol patch).
  • Use of a vaginal ring might not be the best option if you have a narrow vagina or frequent vaginal infections.
  • The ring can fall out without you noticing.
  • Only available as brand name, so it may be expensive if not covered by insurance.
  • All estrogen therapies increase your risk of uterine cancer, heart problems, and blood clots – especially if you have a history of these conditions.
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Used for
  • Hot flashes and night sweats
  • Vaginal dryness and inflammation
  • Low estrogen
  • Ovarian failure
  • Prevention of postmenopausal osteoporosis
Dosage forms
  • Patch
  • Vaginal ring
Price
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Reviews
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31 reviews so far
39%
saidit'sworth it
16%
saiditworked well
19%
saidit'sa big hassle

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Side effects
16possible side effects
  • Breast pain
    28%
  • Lung infection
    17%
  • Stomach pain
    16%
  • Headache
    13%
  • Pain
    11%
  • Swelling of arms and legs
    10%
  • Back pain
    9%
  • Depression
    8%
  • Gas
    7%
  • White or yellow vaginal discharge
    7%
  • Sore throat
    7%
  • Nausea
    6%
  • Stuffy nose
    6%
  • Joint pain
    5%
  • Sinus infection
    5%
  • Itchiness
    3%
See more detailed side effects
8possible side effects
  • Spotting
    8%
  • Headache
    7%
  • Bloating
    7%
  • Vaginal yeast infection
    6%
  • Breast tenderness
    6%
  • Back pain
    6%
  • Sinus infection
    2%
  • Pain in the uterus
    2%
See more detailed side effects
Risks and risk factors
  • Endometrial cancer
    • Using estrogen for more than one year
  • Breast cancer
    • Personal or family history of breast cancer
    • Using estrogen for more than one year
  • Increased risk of blood clots and stroke
    • Personal or family history of blood clots
    • Smoking
    • Obesity
    • Systemic lupus erythematosus (SLE)
  • Increased risk of heart disease
    • Smoking
    • Obesity
    • High blood pressure
    • High blood sugar
    • High cholesterol
    • Age 50 or older
  • Dementia
    • Age 65 or older
  • Pancreas swelling (pancreatitis)
    • High levels of triglycerides
See more detailed risks and warnings
  • Uterine cancer
    • Using estrogen for more than one year
    • Higher dose of estrogen
  • Breast cancer
    • Personal or family history of breast cancer
    • Using estrogen and progestin for more than one year
  • Blood clots and stroke
    • Personal or family history of blood clots
    • Smoking
    • Obesity
    • Systemic lupus erythematosus (SLE)
  • Heart disease
    • Smoking
    • Obesity
    • High blood pressure
    • High blood sugar
    • High cholesterol
    • Age 50 or older
  • Dementia
    • Age 65 or older
  • Inflammation of pancreas
    • High levels of triglycerides
See more detailed risks and warnings