Compare Clindesse vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats bacterial vaginal infections with a single dose.

Clindesse (clindamycin) treats vaginal infections and is very easy to use.

Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

3.6/ 5 average rating with 473 reviewsforBactrim
Upsides
  • Very easy to use and works within a few days.
  • Generic available, so cost is lower.
  • Doesn't have many side effects.
  • You can stand up and walk around right after you use it, so you can use it at any time of day.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • Can cause yeast infections in some women.
  • After using Clindesse (clindamycin), must avoid sex and using tampons for 7 days.
  • Can very rarely cause severe diarrhea.
  • Cannot be used if you have bowel diseases like Crohn's disease or ulcerative colitis.
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
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Used for
Dosage forms
  • Cream
  • Pill
  • Liquid
Price
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Reviews
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473 reviews so far
59%
saidit'sworth it
49%
saiditworked well
22%
saidit'sa big hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

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Side effects
5possible side effects
  • Yeast infection
    14%
  • Headache
    7%
  • Back pain
    5%
  • Constipation
    2%
  • Bladder infection
    2%
See more detailed side effects
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Allergy alert
    • Known allergy to clindamycin
    • Known allergy to lincosamides
  • Severe diarrhea
    • History of Clostridium difficile-associated diarrhea
    • Crohn's disease
    • Ulcerative colitis
    • Regional enteritis
  • Weakened condoms and vaginal diaphragms
  • Safety in girls who haven't started puberty
See more detailed risks and warnings
  • Diarrhea
  • Sunburn
  • Rash
  • Harm to fetus
  • Lower kidney function
    • Elderly
    • Taking other medicines that lower kidney function
See more detailed risks and warnings