Compare Clomid vs. Bravelle

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Clomid (clomiphene)

Prescription only

Bravelle (urofollitropin)

Prescription only
Helps women to ovulate and get pregnant.

Clomid (clomiphene) works well for women who cannot get pregnant because they are not ovulating.

Helps women get pregnant.

Bravelle (urofollitropin) is effective at helping women conceive, but it requires multiple injections to be given at specific days and times.

Upsides
  • One of the few fertility medicines available as a pill rather than injection.
  • Available as a generic product and is less costly than other fertility medicines.
  • Effective for women who are not ovulating or have a condition called polycystic ovary syndrome.
  • One form of Bravelle (urofollitropin) can be given at home in the belly very similar to insulin.
  • More effective at causing successful pregnancies than other medications like it.
  • There is a savings program available to help with the cost.
Downsides
  • A pelvic exam and pregnancy test are necessary before each use of Clomid (clomiphene).
  • Not a good option if you have issues with your liver.
  • Not safe for women with ovarian cysts or enlarged ovaries (aside from polycystic ovary syndrome).
  • Not safe for long-term use. Your doctor will only prescribe Clomid (clomiphene) for a very short time period.
  • Only available as an injection.
  • Depending on which type of injection you get, you may need to make multiple trips to a doctor's office to have Bravelle (urofollitropin) injected.
  • Only available as brand name, so it is very expensive.
  • Is usually only prescribed by certain doctors.
  • Higher rate of miscarriage compared to other fertility treatments.
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Used for
Dosage forms
  • Pill
  • Injection
Price
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Reviews
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Side effects
6possible side effects
  • Ovarian enlargement
    14%
  • Hot flashes
    10%
  • Stomach/pelvic bloating or discomfort
    6%
  • Nausea and vomiting
    2%
  • Breast discomfort
    2%
  • Vision changes or blurring
    2%
See more detailed side effects
23possible side effects
  • Abdominal cramps
    14%
  • Headache
    13%
  • Nausea
    9%
  • Pain after egg harvesting
    8%
  • Abdominal bloating
    7%
  • Overstimulation of ovaries
    6%
  • Heavy vaginal bleeding
    5%
  • Abdominal pain
    5%
  • Pain
    5%
  • Breathing problems
    4%
  • Injection site reaction
    4%
  • Hot flashes
    4%
  • Uterine muscle spasms
    3%
  • Vaginal bleeding
    3%
  • Urinary tract infection
    3%
  • Vaginal discharge
    3%
  • Skin rash
    3%
  • Ovarian disorder
    2%
  • Breast tenderness
    2%
  • Yeast infections
    2%
  • Constipation
    2%
  • Sinus infection
    2%
  • Mood changes
    2%
See more detailed side effects
Risks and risk factors
  • Low blood pressure due to drug interactions
    • Taking interacting medicines, herbal products, and foods
  • Liver problems
    • Current liver disease
    • History of liver disease or damage
  • Unusual uterine bleeding
  • Ovarian cysts
  • Uncontrolled thyroid or adrenal problems
    • Thyroid problems
    • Adrenal gland problems
    • Pituitary tumor
  • Vision changes or blurring
    • Long-term use of Clomid (clomiphene)
  • Ovarian Hyperstimulation Syndrome (OHSS)
    • Long-term use of Clomid (clomiphene)
See more detailed risks and warnings
  • Abnormal enlargement of ovaries
    • High doses
    • Longer length of treatments
  • Ovarian Hyperstimulation Syndrome (OHSS)
    • Pregnancy
  • Lung and blood vessel complications
    • Personal or family history of blood clots
    • Smoking
    • Obesity
    • Ovarian Hyperstimulation Syndrome (OHSS)
  • Ovarian twisting
    • Ovarian Hyperstimulation Syndrome (OHSS)
    • Pregnancy
    • Previous abdominal surgery
    • Personal history of ovarian twisting
    • Personal history of or current ovarian cysts
    • Polycystic Ovarian Syndrome (PCOS)
  • Conception of multiple fetuses
  • Problems during pregnancy
See more detailed risks and warnings