Compare Clotrimazole vs. Jublia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats toenail fungus.

Jublia is good for treating toe nail fungus when over-the-counter treatments have failed, but you will need to use it everyday for 48 weeks and it is very expensive.

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  • There are discount programs that can help with cost of Jublia (efinaconazole). Ask your local pharmacy.
  • Jublia (efinaconazole) may work better than over-the-counter products for toenail fungus.
  • Jublia (efinaconazole) has fewer side-effects than anti-fungal medicines taken orally.
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  • There are other anti-fungal nail solutions that work just as well and cost less than Jublia (efinaconazole).
  • Anti-fungal nail solutions like Jublia (efinaconazole) don't work well to treat severe cases.
  • Like other anti-fungal nail solutions, you will need to use it daily for close to a year.
  • Jublia (efinaconazole) can cause ingrown toenails.
  • Not all toenail fungus need to be treated. Talk to your doctor to see if you require any medicines for your infection.
Used for
  • Candidal vulvovaginitis Candidiasis
  • Topical Oropharyngeal candidiasis Oropharyngeal candidiasis; Prophylaxis Pityriasis versicolor Tinea corporis Tinea cruris Tinea pedis
  • Candidal vulvovaginitis
  • Recurrent; Prophylaxis
  • Toe nail fungus
Dosage forms
  • Cream, gel, or ointment
  • Topical
  • Spray
  • Topical
  • Lozenge
  • Topical solution
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Side effects
The Lotrimin (Clotrimazole) FDA package insert doesn’t have numbers about how common side effects are.
3possible side effects
  • Ingrown toenail
  • Application site irritated skin
  • Application site blisters
See more detailed side effects
Risks and risk factors
No information currently available
  • Ingrown nail
  • Application site skin irritation
  • Application site blisters
  • Application site pain
See more detailed risks and warnings