Compare Clotrimazole vs. Ketoconazole

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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No information currently available
Treats fungal infections.

Nizoral (Ketoconazole) is a medication used on your skin to treat fungal infections; however, it takes several weeks for full recovery, and the directions are specific to each type of medication.

Upsides
No information currently available
  • Recommended as a first choice medication to treat skin infections caused by fungi, including cradle cap, seborrheic dermatitis, and tinea versicolor.
  • Nizoral (Ketoconazole) isn't taken orally, so it doesn't cause liver issues.
  • Can be used with other medications to help control redness and swelling.
  • The 1% shampoo is available over-the-counter in the drugstore.
Downsides
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  • The foams (Extina and Ketodan) and gel (Xolegel) are only available as brand name and can be more expensive.
  • The 2.5% shampoo and creams are available only by prescription, but are generic.
  • The shampoo has to be left on for at least 5-10 minutes after lathering before you rinse it off.
  • It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
  • The fungal infections can be confused for other skin infections, so if Nizoral (Ketoconazole) doesn't work, it could be caused by another skin problem.
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Used for
  • Candidal vulvovaginitis Candidiasis
  • Topical Oropharyngeal candidiasis Oropharyngeal candidiasis; Prophylaxis Pityriasis versicolor Tinea corporis Tinea cruris Tinea pedis
  • Candidal vulvovaginitis
  • Recurrent; Prophylaxis
Dosage forms
  • Cream, gel, or ointment
  • Topical
  • Spray
  • Topical
  • Lozenge
  • Pill
  • Cream, gel, or ointment
  • Foam
  • Shampoo
Price
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Reviews
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Side effects
The Lotrimin (Clotrimazole) FDA package insert doesn’t have numbers about how common side effects are.
1possible side effects
  • Any side effect
    5%
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Risks and risk factors
No information currently available
  • Severe allergic reactions
    • Asthma
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