Compare Clozaril vs. Fanapt

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Clozaril (clozapine)

Prescription only

Fanapt (Iloperidone)

Prescription only
Helps control your thoughts and actions.

Clozaril (clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get regular blood work done because it can have very serious side effects.

Controls schizophrenia.

Fanapt (Iloperidone) is helpful for treating schizophrenia, but it can be expensive because it's only available as brand name.

Upsides
  • Studies show that Clozaril (clozapine) effectively treats schizophrenia when other medications have failed. Clozaril (clozapine) also reduces risk of suicidal behavior.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Safer than other similar medicines during pregnancy.
  • Available as a generic, which is cheaper.
  • Part of the first choice medications to treat schizophrenia.
  • There are patient assistance programs that can lower the copay.
  • Comes in many different strengths to make it easier to customize your dose.
  • Less likely to cause sexual problems than other similar medicines.
Downsides
  • You need to get blood work done every time you get a prescription filled for Clozaril (clozapine). Once it is ready at the pharmacy, you need to pick it up within 7 days.
  • You can only get Clozaril (clozapine) at certain pharmacies that are registered to provide it.
  • You need to limit the amount of alcohol you drink while taking Clozaril (clozapine).
  • Clozaril (clozapine) can cause high blood sugar, high cholesterol, and weight gain.
  • May not be optimal for someone with a history of seizures.
  • Fanapt (Iloperidone) can be expensive because it is only available as brand name.
  • You will need to follow a strict schedule the first two weeks as body adjusts to Fanapt (Iloperidone). You might have to see your doctor several times until you find a dose that works best for you.
  • You're more likely to have changes in blood pressure with Fanapt (Iloperidone), which can make you feel faint or dizzy.
  • If you stop taking Fanapt (Iloperidone) for 3 days and want to restart it, you'll have to start taking it from the beginning dose.
  • You have to take Fanapt (Iloperidone) twice a day, which can be hard to remember.
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Used for
  • Schizophrenia
  • Suicidal behavior in schizophrenia
  • Psychosis in Parkinson's disease
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Pill
Price
No pricing information available
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Reviews
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Side effects
31possible side effects
  • Drowsiness/sedation
    39%
  • Salivation
    31%
  • Fast heartbeat
    25%
  • Dizziness/vertigo
    19%
  • Constipation
    14%
  • Low blood pressure
    9%
  • Headache
    7%
  • Tremor
    6%
  • Fainting
    6%
  • Sweating
    6%
  • Dry mouth
    6%
  • Nausea
    5%
  • Vision problems
    5%
  • Fever
    5%
  • Disturbed sleep/nightmares
    4%
  • Restlessness
    4%
  • Loss of muscle movement
    4%
  • Agitation
    4%
  • High blood pressure
    4%
  • Stomach discomfort/heartburn
    4%
  • Weight gain
    4%
  • Seizures (convulsions)
    3%
  • Rigidity
    3%
  • Confusion
    3%
  • Nausea/vomiting
    3%
  • Low white blood cells
    3%
  • Fatigue
    2%
  • Trouble sleeping
    2%
  • Diarrhea
    2%
  • Problems urinating
    2%
  • Rash
    2%
See more detailed side effects
20possible side effects
  • Dizziness
    10%
  • Sleepiness
    9%
  • Dry mouth
    8%
  • Nausea
    7%
  • Diarrhea
    5%
  • Difficulty controlling movements
    5%
  • Agitation
    5%
  • Nasal congestion
    5%
  • Fatigue
    4%
  • Sore throat
    4%
  • Joint pain
    3%
  • Faster heart rate
    3%
  • Blurred vision
    3%
  • Tremor
    3%
  • Sluggishness
    3%
  • Rash
    3%
  • Sudden changes in blood pressure
    3%
  • Colds or flu
    2%
  • Ejaculation disorder
    2%
  • Difficulty breathing
    2%
See more detailed side effects
Risks and risk factors
  • Low white blood cells
  • Low blood pressure, slow heartbeat, and fainting
    • Dehydration
    • Taking blood pressure medications
    • Heart failure
  • Seizures
    • Seizure disorder
    • Alcohol abuse
  • Heart problems
    • History of heart problems
  • Increased risk of death in elderly with dementia
    • Over 65 with dementia
  • High blood sugar, high cholesterol, and weight gain
See more detailed risks and warnings
  • Increased risk of death
    • People over 65 with dementia and psychosis
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Higher blood sugar, cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
  • Difficulty controlling movements
    • Long-term use of atypical antipsychotics
  • Blood disorders
  • Changes in blood pressure and heart beat
    • High blood pressure
    • History of heartbeat problems
See more detailed risks and warnings