Compare Clozaril vs. Geodon

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Clozaril (Clozapine)

Prescription only

Geodon (ziprasidone)

Prescription only
Helps control your thoughts and actions.

Clozaril (Clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get blood work done regularly and might gain weight.

Helps control your thoughts and mood.

Geodon (ziprasidone) treats bipolar disorder and schizophrenia with fewer side effects than similar medications, but has a risk of abnormal heart rhythm.

3.4/ 5 average rating with 23 reviewsforGeodon
Upsides
  • Clinical studies show that Clozaril (Clozapine) is effective in treating schizophrenia when other medications have failed.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (Clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Available as a generic, which is cheaper.
  • Geodon (ziprasidone) effectively stabilizes mood in schizophrenia and bipolar disorder.
  • Compared to other antipsychotics, this drug has a lower risk of weight gain, high blood sugars, and high cholesterol.
  • Geodon (ziprasidone) capsule is available as a generic.
  • Available as a daily pill for long-term treatment.
Downsides
  • You need to get blood work done every time you can get a prescription filled for Clozaril (Clozapine).
  • You can only get Clozaril (Clozapine) at certain pharmacies that are registered to provide it.
  • If you don't get Clozaril (Clozapine) within 7 days of it being ready at the pharmacy, then you have to get blood work done again and get a new prescription from your doctor.
  • You need to limit the amount of alcohol you drink while on Clozaril (Clozapine).
  • It may take several weeks before you feel the full effects of Geodon (ziprasidone).
  • Might not be a good option if you have a history of heart problems.
  • You will need to get blood tests before you start taking Geodon (ziprasidone) to make sure you're healthy enough to take it.
  • People who are also taking diuretics will need regular blood tests while on Geodon (ziprasidone).
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Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Pill
Price
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Reviews
Not enough review data.Leave a review
23 reviews so far
43%
saidit'sworth it
43%
saiditworked well
30%
saidit'sa big hassle

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Side effects
33possible side effects
  • Drowsiness/Sedation
    39%
  • Salivation
    31%
  • Tachycardia
    25%
  • Dizziness/Vertigo
    19%
  • Constipation
    14%
  • Hypotension
    9%
  • Headache
    7%
  • Tremor
    6%
  • Syncope
    6%
  • Sweating
    6%
  • Dry Mouth
    6%
  • Nausea
    5%
  • Visual Disturbances
    5%
  • Fever
    5%
  • Disturbed Sleep/Nightmares
    4%
  • Restlessness
    4%
  • Hypokinesia/Akinesia
    4%
  • Agitation
    4%
  • Hypertension
    4%
  • Abdominal Discomfort/Heartburn
    4%
  • Weight Gain
    4%
  • Seizures (convulsions)
    3%
  • Rigidity
    3%
  • Akathisia
    3%
  • Confusion
    3%
  • Nausea/Vomiting
    3%
  • Vomiting
    3%
  • Leukopenia/Decreased WBC/Neutropenia
    3%
  • Fatigue
    2%
  • Insomnia
    2%
  • Diarrhea
    2%
  • Urinary Abnormalities
    2%
  • Rash
    2%
See more detailed side effects
23possible side effects
  • Sleepiness
    31%
  • Movement problems
    31%
  • Headache
    18%
  • Dizziness
    16%
  • Nausea
    10%
  • Restlessness
    10%
  • Weakness
    6%
  • Abnormal vision
    6%
  • Diarrhea
    5%
  • Dry mouth
    5%
  • Vomiting
    5%
  • Anxiety
    5%
  • Accidental injury
    4%
  • Increased salivation
    4%
  • High blood pressure
    3%
  • Tongue swelling
    3%
  • Sore throat
    3%
  • Difficulty swallowing
    2%
  • Muscle pain
    2%
  • Loss of sensation
    2%
  • Speech disorder
    2%
  • Shortness of breath
    2%
  • Itchy, red skin
    2%
See more detailed side effects
Risks and risk factors
  • Fewer white blood cells
  • Low blood pressure | Slow heartbeat | Fainting
    • Dehydration
    • Taking blood pressure medications
  • Seizures
    • Seizure disorder
    • Alcohol abuse
  • Heart problems
    • History of heart problems
  • Increased risk of death
    • Over 65 and having dementia
  • Weight gain
  • Increased blood sugar
    • Diabetes
  • Increased cholesterol
  • Neuroleptic malignant syndrome (NMS)
  • Tardive dyskinesia
  • Return of schizophrenic symptoms
    • Stopping Clozaril (Clozapine) suddenly
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Heart problems
    • History of heart problems
    • Taking other drugs that also cause heart rhythm changes
    • Low potassium
    • Low magnesium
  • Neuroleptic malignant syndrome (NMS)
  • Abnormal and involuntary muscle movements
    • Taking Geodon (ziprasidone) in higher doses or for a long time
    • Elderly women
  • Dizziness and falls
    • Dehydration
    • Taking blood pressure medications
    • History of heart disease
See more detailed risks and warnings