Compare Clozaril vs. Latuda

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Clozaril (clozapine)

Prescription only

Latuda (lurasidone)

Prescription only
Helps control your thoughts and actions.

Clozaril (clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get regular blood work done because it can have very serious side effects.

Helps control your thoughts and mood.

Latuda (lurasidone) is good for treating schizophrenia and depression related to bipolar disorder, but can cause sleepiness and movement disorders that can affect your ability to stay alert.

3.8/ 5 average rating with 61 reviewsforLatuda
Upsides
  • Studies show that Clozaril (clozapine) effectively treats schizophrenia when other medications have failed. Clozaril (clozapine) also reduces risk of suicidal behavior.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Safer than other similar medicines during pregnancy.
  • Available as a generic, which is cheaper.
  • Has been shown in clinical studies to help people experience improvement in their thoughts and mood.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotic medicines, Latuda (lurasidone) has a lower risk of causing weight gain, high cholesterol, high blood sugar, and heart rhythm changes.
Downsides
  • You need to get blood work done every time you get a prescription filled for Clozaril (clozapine). Once it is ready at the pharmacy, you need to pick it up within 7 days.
  • You can only get Clozaril (clozapine) at certain pharmacies that are registered to provide it.
  • You need to limit the amount of alcohol you drink while taking Clozaril (clozapine).
  • Clozaril (clozapine) can cause high blood sugar, high cholesterol, and weight gain.
  • May not be optimal for someone with a history of seizures.
  • It may take several weeks before you feel the full effects of Latuda (lurasidone).
  • You may get more side effects if you're taking certain antifungal and heart medicines.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (lurasidone).
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Used for
  • Schizophrenia
  • Suicidal behavior in schizophrenia
  • Psychosis in Parkinson's disease
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Pill
Price
Lowest price
$1223.39
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Reviews
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61 reviews so far
61%
saidit'sworth it
61%
saiditworked well
25%
saidit'sa big hassle

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Side effects
31possible side effects
  • Drowsiness/sedation
    39%
  • Salivation
    31%
  • Fast heartbeat
    25%
  • Dizziness/vertigo
    19%
  • Constipation
    14%
  • Low blood pressure
    9%
  • Headache
    7%
  • Tremor
    6%
  • Fainting
    6%
  • Sweating
    6%
  • Dry mouth
    6%
  • Nausea
    5%
  • Vision problems
    5%
  • Fever
    5%
  • Disturbed sleep/nightmares
    4%
  • Restlessness
    4%
  • Loss of muscle movement
    4%
  • Agitation
    4%
  • High blood pressure
    4%
  • Stomach discomfort/heartburn
    4%
  • Weight gain
    4%
  • Seizures (convulsions)
    3%
  • Rigidity
    3%
  • Confusion
    3%
  • Nausea/vomiting
    3%
  • Low white blood cells
    3%
  • Fatigue
    2%
  • Trouble sleeping
    2%
  • Diarrhea
    2%
  • Problems urinating
    2%
  • Rash
    2%
See more detailed side effects
12possible side effects
  • Nausea
    14%
  • Sleepiness
    11%
  • Restlessness
    9%
  • Movement disorder
    7%
  • Dry mouth
    5%
  • Vomiting
    4%
  • Diarrhea
    4%
  • Common cold
    4%
  • Anxiety
    4%
  • Flu
    2%
  • Urinary tract infection
    2%
  • Back pain
    2%
See more detailed side effects
Risks and risk factors
  • Low white blood cells
  • Low blood pressure, slow heartbeat, and fainting
    • Dehydration
    • Taking blood pressure medications
    • Heart failure
  • Seizures
    • Seizure disorder
    • Alcohol abuse
  • Heart problems
    • History of heart problems
  • Increased risk of death in elderly with dementia
    • Over 65 with dementia
  • High blood sugar, high cholesterol, and weight gain
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Abnormal and involuntary muscle movements
    • Taking Latuda (lurasidone) in higher doses or for a long time
    • Elderly
    • Female
  • Low blood pressure
    • Dehydration
    • Taking blood pressure medications
  • Sedation and driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Low white blood cells
See more detailed risks and warnings