Compare Clozaril vs. Seroquel
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps control your thoughts and actions.
Clozaril (clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get regular blood work done because it can have very serious side effects.
Helps control your thoughts and mood.
Seroquel (quetiapine) is a effective at treating schizophrenia, mania, and depression but it can cause weight gain and high blood glucose levels.
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3.7/ 5 average rating with 250 reviewsforSeroquel
Upsides
- Studies show that Clozaril (clozapine) effectively treats schizophrenia when other medications have failed. Clozaril (clozapine) also reduces risk of suicidal behavior.
- Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
- Clozaril (clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
- Safer than other similar medicines during pregnancy.
- Available as a generic, which is cheaper.
- Seroquel (quetiapine) is effective at relieving psychotic symptoms and manic episodes.
- Seroquel (quetiapine) has fewer side effects than most antipsychotic medications.
- Seroquel (quetiapine) is less likely to cause heart problems compared to some other antipsychotics.
- Seroquel (quetiapine) is also the least likely to cause Extrapyramidal Symptoms (EPS) – a movement disorder that causes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
Downsides
- You need to get blood work done every time you get a prescription filled for Clozaril (clozapine). Once it is ready at the pharmacy, you need to pick it up within 7 days.
- You can only get Clozaril (clozapine) at certain pharmacies that are registered to provide it.
- You need to limit the amount of alcohol you drink while taking Clozaril (clozapine).
- Clozaril (clozapine) can cause high blood sugar, high cholesterol, and weight gain.
- May not be optimal for someone with a history of seizures.
- Seroquel (quetiapine) has a moderate to high risk of weight gain, elevated cholesterol and/or blood sugar compared to other antipsychotics.
- You might need routine blood tests to check how Seroquel (quetiapine) is affecting your body.
Used for
- Schizophrenia
- Suicidal behavior in schizophrenia
- Psychosis in Parkinson's disease
Dosage forms
- Pill
- Dissolving tablet
- Liquid
- Pill
- Extended release
Price
Lowest price
$766.92
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$20.79
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Reviews
Not enough review data.Leave a review
250 reviews so far
56%
saidit'sworth it
50%
saiditworked well
27%
saidit'sa big hassle
Have you used Seroquel (quetiapine)?
Leave a reviewSide effects
31possible side effects
- Drowsiness/sedation39%
- Salivation31%
- Fast heartbeat25%
- Dizziness/vertigo19%
- Constipation14%
- Low blood pressure9%
- Headache7%
- Tremor6%
- Fainting6%
- Sweating6%
- Dry mouth6%
- Nausea5%
- Vision problems5%
- Fever5%
- Disturbed sleep/nightmares4%
- Restlessness4%
- Loss of muscle movement4%
- Agitation4%
- High blood pressure4%
- Stomach discomfort/heartburn4%
- Weight gain4%
- Seizures (convulsions)3%
- Rigidity3%
- Confusion3%
- Nausea/vomiting3%
- Low white blood cells3%
- Fatigue2%
- Trouble sleeping2%
- Diarrhea2%
- Problems urinating2%
- Rash2%
36possible side effects
- Drowsiness34%
- Dry mouth19%
- Headache17%
- Weakness10%
- Constipation10%
- Dizziness9%
- Tremor8%
- Stomach pain7%
- Low blood pressure7%
- Agitation6%
- Weight gain6%
- Sore throat6%
- Back pain5%
- Stiffness/difficulty moving4%
- Hay fever4%
- Swelling in the limbs4%
- Twitching4%
- Indigestion4%
- Depression3%
- Lazy eye3%
- Speech disorder3%
- Altered hormone levels3%
- Heaviness2%
- Infection2%
- Fever2%
- High blood pressure2%
- Increased heart rate2%
- Increased appetite2%
- Hypothyroidism2%
- Incoordination2%
- Abnormal thinking2%
- Anxiety2%
- Loss of control of movements2%
- Sinus infection2%
- Sweating2%
- Urinary Tract Infection2%
Risks and risk factors
- Low white blood cells
- Low blood pressure, slow heartbeat, and fainting
- Dehydration
- Taking blood pressure medications
- Heart failure
- Seizures
- Seizure disorder
- Alcohol abuse
- Heart problems
- History of heart problems
- Increased risk of death in elderly with dementia
- Over 65 with dementia
- High blood sugar, high cholesterol, and weight gain
- Higher risk of death
- Elderly patients with dementia-related psychosis
- Suicidal thoughts or behavior
- Children, adolescents, and young adults (<24 years old)
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Extrapyramidal Symptoms (EPS)
- Metabolic changes (increased blood sugar, high cholesterol and weight gain)
- People with diabetes
- People with high cholesterol