Compare Colcrys vs. Uloric
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Prevents and treats gout.
Colcrys (colchicine) is a second-choice treatment for gout attacks. Be careful how much you use since it can cause problems with your blood.
Stops gout attacks.
Uloric (febuxostat) is a medication you take once daily for gout, but it takes a few weeks to kick in.
- Colcrys (colchicine) treats and stops sudden gout attacks.
- It can be used to prevent gout when people are first starting on allopurinol.
- Colcrys (colchicine) also treats Familial Mediterranean fever.
- Uloric (febuxostat) can be used to lower uric acid if Zyloprim (allopurinol) doesn't work.
- You only need to take Uloric (febuxostat) once a day.
- People with mild to moderate kidney disease can use Uloric (febuxostat).
- Colcrys (colchicine) doesn't work as well as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids to treat gout attacks.
- Taking Colcrys (colchicine) for too long can cause problems with your blood.
- Doses needs to be changed if you have kidney or liver problems.
- While Colcrys (colchicine) stops the redness and swelling of gout attacks, it doesn't stop the pain.
- If you're taking Colcrys (colchicine) to stop gout flare-ups, you can only use it for 3 to 6 months after your levels have stabilized.
- The capsules (Mitigare) are only approved for prevention, but not treatment of gout.
- You can have more gout attacks in the first few weeks of taking Uloric (febuxostat).
- While taking Uloric (febuxostat), you need to drink a lot of fluids to stop kidney stones from forming.
- You'll have to get your blood checked often with Uloric (febuxostat) therapy.
- Uloric (febuxostat) doesn't come in generic, so it can be more expensive.
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5possible side effects
- Stomach problems26%
- Throat pain3%
The Uloric (febuxostat) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Blood disorders
- Death from overdose
- Food and medicine interactions
- Grapefruit juice
- Protease inhibitors
- Antifungal antibiotics
- Calcium channel blockers
- Anti-cholesterol medicines
- Muscle pain and breakdown
- Kidney problems
- Use of statins or cholesterol medications
- Use of cyclosporine
- Gout flare-ups
- Blood clots
- History of stroke or heart attack
- Liver problems
- Allergic reaction
- History of skin reaction to allopurinol