Compare Combipatch vs. Aygestin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats low estrogen and relieves menopause symptoms.
Combipatch (estradiol / norethindrone patch) is a twice weekly patch that effectively treats menopause and causes less blood clots or stroke than combination pills.
Regulates your menstrual cycle and treats irregular bleeding.
Aygestin (norethindrone) regulates the menstrual cycle and treats heavy or irregular vaginal bleeding. It's easy to take and isn't expensive.
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2.7/ 5 average rating with 30 reviewsforAygestin
Upsides
- Twice weekly patch. Good for people who don't want to take daily pills.
- Replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness).
- Less likely to cause blood clots or stroke than pills since patches contain a lower amount of hormones.
- Good for women with an intact uterus.
- You can bathe, shower, and swim while wearing the patch, as long as you don't rub the patch.
- Helps to regulate your period.
- Decreases bleeding from hormone imbalance.
- Available as a generic medication, so it costs less.
Downsides
- More potential side effects than single ingredient medications since it exposes your whole body to two hormones.
- You may get irregular bleeding and spotting that can last a few months to a year.
- The patch can't be exposed to direct sunlight for long periods of time.
- Can be expensive since it's only available as a brand name product.
- Can make you gain weight.
- Higher risk of blood clots.
- Not for people who are post-menopausal, pregnant, or breast-feeding.
- Can cause a lot of side effects.
Used for
- Hot flashes
- Vaginal dryness and inflammation
- Low estrogen
- Primary ovarian failure
- Pain caused by endometriosis
- Balances hormones in women who don't have regular monthly periods
- Balances hormones in women who have unusual monthly periods
- In vitro fertilization
Dosage forms
- Patch
- Pill
Price
Lowest price
$181.68
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$28.62
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Reviews
Not enough review data.Leave a review
30 reviews so far
40%
saidit'sworth it
23%
saiditworked well
23%
saidit'sa big hassle
Have you used Aygestin (norethindrone)?
Leave a reviewSide effects
24possible side effects
- Breast pain25%
- Menstrual cramps20%
- Headache18%
- Back pain11%
- Nausea11%
- Flu like symptoms9%
- Weakness8%
- Abnormal pap smear8%
- Stomach pain7%
- Lung problems7%
- Stuffy nose7%
- Pain6%
- Menstrual problems6%
- Vaginal inflammation6%
- Vaginal discharge5%
- Accidental injury4%
- Diarrhea4%
- Gas4%
- Sore throat4%
- Sinus infection4%
- Depression3%
- Trouble sleeping3%
- Nervousness3%
- Skin irritation2%
The Aygestin (norethindrone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Endometrial cancer
- Using estrogen for more than one year
- Breast cancer
- Personal or family history of breast cancer
- Using estrogen for more than one year
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Systemic lupus erythematosus (SLE)
- Dementia
- Aged 65 or older
- Pancreas swelling (pancreatitis)
- High levels of triglycerides
- Gallbladder problems
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Systemic lupus erythematosus (SLE)
- Abnormal vision changes
- Depression
- History of depression
- Changes in blood sugar levels
- Diabetes
- Liver problems
- History of liver problems
- High cholesterol levels
- High cholesterol levels