Compare Combivent vs. Spiriva Respimat

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Makes it easier to breathe.

Combivent (ipratropium / albuterol) is effective for people who need 2 medications to control their COPD symptoms, but has to be used 4 times a day.

3.4/ 5 average rating with 142 reviewsforCombivent
Helps you breathe easier.

Spiriva Respimat (tiotropium) works well to reduce breathing problems and open your airways, but it can't help you if you're having sudden wheezing or breathing problems.

  • Effectively relieves symptoms of COPD.
  • The Respimat inhaler doesn't require shaking before use, and only 1 inhalation per dose is needed.
  • The nebulizer solution comes in a generic form and is much cheaper than the inhaler.
  • Spiriva Respimat (tiotropium) is a good choice to help you breathe easier and lessen the need for a fast-acting (rescue) inhaler.
  • If you're using Spiriva Respimat (tiotropium) for asthma, your asthma can get better if you use Spiriva Respimat (tiotropium) consistently every day.
  • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
  • Used once daily.
  • Compared to Spiriva, Spiriva Respimat (tiotropium) allows more medicine to enter your lungs and doesn't require as much force to inhale.
  • No generic form of the inhaler is currently available, so it can be very expensive for people without insurance.
  • Can make your heart beat faster, which is an uncomfortable side effect. Might not be a good option for those with heart problems since the medicine can raise your heart rate and blood pressure.
  • Can raise eye pressure and worsen symptoms for people who have a certain type of glaucoma.
  • Can cause problems with urinating, so might not be appropriate for those with an enlarged prostate.
  • Using Spiriva Respimat (tiotropium) only slows the progression of your condition, Spiriva Respimat (tiotropium) won't cure you.
  • You'll need to use this medicine consistently every day to gain the most benefit.
  • Spiriva Respimat (tiotropium) can worsen your symptoms of an enlarged prostate or urinary blockage.
  • Spiriva Respimat (tiotropium) can worsen a certain type of glaucoma.
Used for
Dosage forms
  • Inhaler
  • Nebulizer solution
  • Inhaler
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142 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

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Side effects
11possible side effects
  • Lung disease
  • Common cold symptoms
  • Sore throat
  • Cough
  • Headache
  • Inflammation of lung airways
  • Infection of airways, nose, and throat
  • Chest pain
  • Shortness of breath
  • Diarrhea
  • Urinary tract infection
See more detailed side effects
4possible side effects
  • Sore throat
  • Headache
  • Sinus infection
  • Bronchitis
See more detailed side effects
Risks and risk factors
  • Sudden-onset difficulty breathing
  • Effects on heart
    • Using more Combivent (ipratropium / albuterol) than recommended
    • People with heart problems
    • People with high blood pressure
    • People with an overactive thyroid
  • Effects on eyes
    • People with a history of narrow-angle glaucoma
  • Difficulty urinating
    • People with a history of urinary blockage
    • People with an enlarged prostate
  • Severe allergic reaction
  • Life-threatening effects
    • Using more Combivent (ipratropium / albuterol) than recommended
See more detailed risks and warnings
  • Not for breathing emergenices
  • Sudden difficulty breathing
  • Worsening glaucoma
    • History of narrow-angle glaucoma
  • Difficulty urinating
    • History of urinary bladder blockage (urinary obstruction)
    • History of enlarged prostate
  • Kidney problems
    • History of moderate to severe kidney disease
See more detailed risks and warnings