Compare Coreg vs. hydrochlorothiazide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Coreg (Carvedilol)

Prescription only
Lowers blood pressure and controls heart rate.

Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.

3.5/ 5 average rating with 406 reviewsforCoreg
Removes water from the body, which lowers blood pressure.

Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.

3.3/ 5 average rating with 139 reviewsforhydrochlorothiazide
Upsides
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
  • Does a good job getting rid of extra fluids in your body by making you urinate more.
  • A first-choice blood pressure treatment. Works especially well for people of African descent.
  • Lowers the risk of heart attack and stroke.
  • Good option if you have high blood pressure and heart failure.
  • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
  • Can be good for patients with osteoporosis since it raises the body's level of calcium.
Downsides
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Makes you urinate more often.
  • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
  • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
  • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
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Reviews
406 reviews so far
53%
saidit'sworth it
46%
saiditworked well
18%
saidit'sa big hassle

Have you used Coreg (Carvedilol)?

Leave a review
139 reviews so far
47%
saidit'sworth it
31%
saiditworked well
16%
saidit'sa big hassle

Have you used Microzide (hydrochlorothiazide (HCTZ))?

Leave a review
Side effects
5possible side effects
  • Dizziness
    6%
  • Bradycardia
    2%
  • Postural hypotension
    2%
  • Insomnia
    2%
  • Diarrhea
    2%
See more detailed side effects
The Microzide (hydrochlorothiazide (HCTZ)) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Worsened chest pain; increased risk of heart attack and heart rhythm problems
    • Abrupt discontinuation of Coreg (Carvedilol)
  • Slowing of the heart rate
  • Low blood pressure
  • Worsening heart failure
    • Congestive heart failure
    • Increasing the dose of Coreg (Carvedilol)
  • Masked symptoms of low blood sugar
    • Diabetes
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Masked symptoms of overactive thyroid
See more detailed risks and warnings
  • Dehydration and electrolyte imbalance
    • Current electrolyte imbalance
    • Lower kidney function
    • Dehydration
  • Severe allergic reactions
    • History of sulfa allergies
  • Gout
    • History of gout
    • Current kidney problems
  • Vision problems
    • History of sulfa or penicillin allergies
  • Higher blood sugars
    • Diabetes
See more detailed risks and warnings