Compare Corlanor vs. Inspra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Corlanor (ivabradine)

Prescription only

Inspra (eplerenone)

Prescription only
Reduces hospitalization due to worsening heart failure.

Corlanor (ivabradine) can help keep you out of hospital, but won't reverse your condition or provide any long-term benefit.

Helps lower blood pressure and protect the heart in people with heart failure.

Inspra (eplerenone) lowers blood pressure and can help remove fluid when it's used with other drugs. It reduces the risk of death in people with heart failure and is usually used when people can't take spironolactone.

Upsides
  • Corlanor (ivabradine) can help slow down your heart rate if you have an arrhythmia.
  • Corlanor (ivabradine) can be used safely by people who are 75 years old and older.
  • Lowers your blood pressure.
  • It can help remove fluid from your body when it's used with other drugs.
  • Reduces the risk of death in people with heart failure.
  • It can have fewer side effects than spironolactone.
Downsides
  • Corlanor (ivabradine) must be taken with food.
  • Not everyone with heart failure should take Corlanor (ivabradine).
  • Only available in brand form and is very expensive if not covered by insurance.
  • Corlanor (ivabradine) interferes with how a lot of medications and supplements work.
  • Inspra (eplerenone) isn't a first choice medicine for lowering blood pressure or getting rid of fluid in the body. It's usually used in combination with other medicines.
  • It can make you feel dizzy for the first few days. Be careful driving until you know how it affects you.
  • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.
  • It can be very expensive compared to spironolactone.
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Reviews
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Side effects
4possible side effects
  • Slow heartbeats
    10%
  • Increased blood pressure
    8%
  • Heart rhythm problems
    8%
  • Seeing colored bright lights
    2%
See more detailed side effects
2possible side effects
  • High potassium
    3%
  • Abnormal renal function
    3%
See more detailed side effects
Risks and risk factors
  • Harm to unborn baby
  • Heart rhythm problems
  • Slow heartbeat
    • Using other heart medicines that slow down your heart rate
    • Certain heart conditions
See more detailed risks and warnings
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
  • Heart problems from high potassium
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
    • Diabetes with proteinuria
  • Breast pain or swelling
  • Kidney problems
    • Current kidney problems
  • Liver problems
    • Liver damage
See more detailed risks and warnings