Compare Coumadin vs. aspirin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Coumadin (warfarin)

Prescription only

Ecotrin (aspirin)

Prescription or OTC
Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

3.8/ 5 average rating with 513 reviewsforCoumadin
Relieves pain, fever, and inflammation.

Ecotrin (aspirin) can be used for pain and fever relief or heart protection, and is generally very safe and affordable.

3.8/ 5 average rating with 533 reviewsforaspirin
Upsides
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
  • Ecotrin (aspirin) provides the best protection for your heart to prevent heart attacks and stroke with the lowest risk of side effects
  • It is available over-the-counter in drugstores on its own and in combination with other cold and flu medications.
  • Ecotrin (aspirin) is available as a cheaper, generic form.
  • Ecotrin (aspirin) is available in several forms, including tablets, chewable tablets, and suppositories.
Downsides
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Ecotrin (aspirin) is not a preferred medication for treating pain, inflammation, or fever due to the high risk of bleeding.
  • Ecotrin (aspirin) increases the risk of bleeding, especially when used with other blood thinner medications like Coumadin (warfarin).
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Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
  • Suppository
Price
No pricing information available
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Reviews
513 reviews so far
61%
saidit'sworth it
54%
saiditworked well
21%
saidit'sa big hassle

Have you used Coumadin (warfarin)?

Leave a review
533 reviews so far
76%
saidit'sworth it
41%
saiditworked well
6%
saidit'sa big hassle

Have you used Ecotrin (aspirin)?

Leave a review
Side effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
The Ecotrin (aspirin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Life threatening bleeding
    • Coumadin (warfarin) dose too high
    • Age greater than 65 year
    • History of stomach bleeding
    • High blood pressure
    • Kidney or liver problems
    • Drug interactions
    • Change in lifestyle or diet
    • Alcohol use
    • Certain genetic factors
  • Harm to fetus
    • Women of childbearing age
  • Drug and diet interactions
  • Potential surgery or amputation
See more detailed risks and warnings
  • Reye's Syndrome in children
    • Children 18 years or younger
    • Children recovering from viral infections
  • Bleeding
    • History of stomach bleeding or ulcers
    • Taking Ecotrin (aspirin), NSAIDs, or blood thinners
    • Alcohol use
    • People 75 years and older taking high dose (325mg) of Ecotrin (aspirin)
  • Serious allergic reactions
    • Allergy to Ecotrin (aspirin)
See more detailed risks and warnings