Compare Coumadin vs. Eliquis
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Prevents blood clots.
Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.
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3.8/ 5 average rating with 513 reviewsforCoumadin
Prevents blood clots.
Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.
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3.8/ 5 average rating with 19 reviewsforEliquis
Upsides
- Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
- In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
- Coumadin (warfarin) comes in numerous strengths.
- Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
- Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
- You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
- If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
Downsides
- Raises your risk of bleeding and bruising.
- Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
- Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
- A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
- You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
- Can't be used if you have artificial heart valves.
- Never stop taking Eliquis (apixaban) without talking to your doctor first.
- Eliquis (apixaban) isn't available as a generic, so it can be expensive.
- If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
Used for
- DVT
- DVT prevention
- Pulmonary embolism
- Pulmonary embolism prevention
- Prevention of repeat heart attack
- Blood clot prevention after heart attack
- Artificial heart valve blood clots (treatment and prevention)
- Atrial fibrillation blood clot (treatment and prevention)
- Atrial fibrillation
- Stroke and blood clot prevention
- Blood clot treatment
Dosage forms
- Pill
- Pill
Price
Lowest price
$14.73
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$448.12
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Reviews
513 reviews so far
61%
saidit'sworth it
54%
saiditworked well
21%
saidit'sa big hassle
Have you used Coumadin (warfarin)?
Leave a review19 reviews so far
47%
saidit'sworth it
58%
saiditworked well
21%
saidit'sa big hassle
Have you used Eliquis (apixaban)?
Leave a reviewSide effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Life threatening bleeding
- Coumadin (warfarin) dose too high
- Age greater than 65 year
- History of stomach bleeding
- High blood pressure
- Kidney or liver problems
- Drug interactions
- Change in lifestyle or diet
- Alcohol use
- Certain genetic factors
- Harm to fetus
- Women of childbearing age
- Drug and diet interactions
- Potential surgery or amputation
- Increased risk of stroke or blood clots from early discontinuation
- Stopping Eliquis (apixaban) prematurely
- Paralysis in the spine
- Spinal puncture (spinal tap)
- Getting anesthesia in the spine (epidural anesthesia)
- History of spinal surgery
- Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), or other blood-thinners
- Interactions with other drugs
- Increased risk of stroke or bleeding
- Artificial heart valve
- Increased side effects in kidney or liver conditions
- Current kidney problems
- Current liver problems