Compare Coumadin vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Coumadin (warfarin)

Prescription only

Pradaxa (dabigatran)

Prescription only
Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

3.8/ 5 average rating with 513 reviewsforCoumadin
Prevents and treats blood clots.

Pradaxa (dabigatran) is an effective oral medicine for preventing and treating blood clots, but it can increase the risk of bleeding especially in older people and those with kidney problems.

Upsides
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
  • Pradaxa (dabigatran) doesn't require regular blood tests or frequent dose changes, unlike Coumadin.
  • Works just as well as other blood thinners in lowering the risk of stroke and heart attacks.
  • In cases of accidental overdose, an antidote is available to reverse the effects of the medicine.
  • May be taken with or without food.
Downsides
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Pradaxa (dabigatran) is not available in generic form so it can be expensive.
  • Might not be a good option for people age 75 or older and those with kidney problems due to the increased risk of bleeding.
  • Not safe to be used in people with artificial heart valves.
  • Pradaxa (dabigatran) is associated with a higher risk of stomach bleeding compared to Coumadin.
  • Might not be appropriate for people who need to take aspirin or NSAIDs (such as ibuprofen) regularly since it can add to the risk of bleeding.
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Reviews
513 reviews so far
61%
saidit'sworth it
54%
saiditworked well
21%
saidit'sa big hassle

Have you used Coumadin (warfarin)?

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Side effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Any bleeding
    11%
  • Non-major bleeding
    5%
See more detailed side effects
Risks and risk factors
  • Life threatening bleeding
    • Coumadin (warfarin) dose too high
    • Age greater than 65 year
    • History of stomach bleeding
    • High blood pressure
    • Kidney or liver problems
    • Drug interactions
    • Change in lifestyle or diet
    • Alcohol use
    • Certain genetic factors
  • Harm to fetus
    • Women of childbearing age
  • Drug and diet interactions
  • Potential surgery or amputation
See more detailed risks and warnings
  • Blood clots
    • Stopping Pradaxa (dabigatran) suddenly
  • Blood clots in the spine
    • People who have done a spinal tap or had a local anesthetic medicine injected into their spine
  • Increased risk of bleeding
    • Taking other medicines that also increase bleeding risk such as NSAIDs, aspirin, or blood thinners
    • People with kidney problems
    • People age 75 or older
  • People with artificial heart valves
    • People with artificial heart valve(s)
See more detailed risks and warnings