Compare Coumadin vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Coumadin (warfarin)

Prescription only

Pradaxa (Dabigatran)

Prescription only
Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

3.8/ 5 average rating with 513 reviewsforCoumadin
Prevents blood clots.

Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.

Upsides
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
  • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
  • Doesn't require regular blood tests or frequent dose changes.
  • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
Downsides
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Not available as generic.
  • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
  • Can't take during pregnancy.
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Price
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Reviews
513 reviews so far
61%
saidit'sworth it
54%
saiditworked well
21%
saidit'sa big hassle

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Side effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • GI side effect
    35%
  • Any side effect
    21%
  • Any bleed
    20%
  • Dyspepsia
    8%
  • Major gastrointestinal bleed
    6%
  • Major bleed
    3%
  • GI bleed
    3%
  • Gastritis-like symptoms
    3%
  • Life-threatening bleed
    2%
  • Gastrointestinal bleed
    2%
See more detailed side effects
Risks and risk factors
  • Life threatening bleeding
    • Coumadin (warfarin) dose too high
    • Age greater than 65 year
    • History of stomach bleeding
    • High blood pressure
    • Kidney or liver problems
    • Drug interactions
    • Change in lifestyle or diet
    • Alcohol use
    • Certain genetic factors
  • Harm to fetus
    • Women of childbearing age
  • Drug and diet interactions
  • Potential surgery or amputation
See more detailed risks and warnings
  • Blood clots
    • Stopping Pradaxa (Dabigatran) too soon
  • Blood clot in the spine
    • Spinal tap
    • Anesthesia along the spine (epidural anesthesia)
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Unusual bleeding
    • Drug interactions
    • Taking with NSAIDs, aspirin, or other blood-thinning medicines
  • Stomach or intestinal problems
  • Increased risk of stroke or bleeding
    • Artificial heart valve
See more detailed risks and warnings