Compare Coumadin vs. Savaysa

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Coumadin (warfarin)

Prescription only

Savaysa (edoxaban)

Prescription only
Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

3.8/ 5 average rating with 513 reviewsforCoumadin
Prevents blood clots.

Savaysa (edoxaban) can prevent blood clots without food restrictions or frequent blood tests. However, its effects will be hard to reverse in the event of an overdose.

  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
  • Works as well as other blood thinners to prevent strokes or blood clots.
  • Does not require frequent blood tests like warfarin.
  • Does not require food restrictions like warfarin.
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Taking Savaysa (edoxaban) raises your risk of bleeding and bruising. If you take Savaysa (edoxaban) along with other anti-inflammatory medicines like aspirin or ibuprofen, this can make you even more likely to bleed and bruise easily.
  • Savaysa (edoxaban) is not available as a generic medicine so it can be quite pricey.
  • You may not be able to concentrate enough drug in your blood if your kidney works really well. Your doctor should check your kidney function before starting treatment.
  • Savaysa (edoxaban) cannot be used in people with mechanical heart valves or valvular atrial fibrillation.
  • There is no antidote for Savaysa (edoxaban).
Used for
  • Prevention of stroke and blood clots in nonvalvular atrial fibrillation
  • Treatment of major blood clots (deep vein thrombosis and pulmonary embolism)
Dosage forms
  • Pill
  • Pill
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
513 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Coumadin (warfarin)?

Leave a review
Not enough review data.Leave a review
Side effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Major bleeding
  • Bleeding of the stomach
See more detailed side effects
Risks and risk factors
  • Life threatening bleeding
    • Coumadin (warfarin) dose too high
    • Age greater than 65 year
    • History of stomach bleeding
    • High blood pressure
    • Kidney or liver problems
    • Drug interactions
    • Change in lifestyle or diet
    • Alcohol use
    • Certain genetic factors
  • Harm to fetus
    • Women of childbearing age
  • Drug and diet interactions
  • Potential surgery or amputation
See more detailed risks and warnings
  • Not enough medicine in your blood
    • Excellent kidney function (filtration rate more than 95 mL/min
  • Blood clots and stroke
    • Stopping Savaysa (edoxaban) too early
    • Mechanical heart valve
    • Narrow mitral valve in the heart
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Taking anti-inflammatory medicines like aspirin and ibuprofen
    • Taking other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings