Compare Coumadin vs. Xarelto
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Prevents blood clots.
Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.
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3.8/ 5 average rating with 513 reviewsforCoumadin
Prevents blood clots.
Xarelto (rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. However, it can be expensive and there's no way to reverse the medication's effects.
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3.5/ 5 average rating with 22 reviewsforXarelto
Upsides
- Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
- In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
- Coumadin (warfarin) comes in numerous strengths.
- Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
- Studies show that Xarelto (rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and stopping clots from froming.
- Xarelto (rivaroxaban) doesn't require regular blood tests or frequent dose changes.
- Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
Downsides
- Raises your risk of bleeding and bruising.
- Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
- Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
- A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
- Xarelto (rivaroxaban) can increase your risk of bleeding, so call your doctor right away if you see blood in your spit, urine, or stool (look for black, tarry stools or bright red blood).
- Xarelto (rivaroxaban) isn't available as a generic medication.
- There are no antidotes to stop bleeding caused by taking too much Xarelto (rivaroxaban).
- You can't take Xarelto (rivaroxaban) if you are pregnant.
Used for
- DVT
- DVT prevention
- Pulmonary embolism
- Pulmonary embolism prevention
- Prevention of repeat heart attack
- Blood clot prevention after heart attack
- Artificial heart valve blood clots (treatment and prevention)
- Atrial fibrillation blood clot (treatment and prevention)
- Atrial fibrillation
- Deep vein thrombosis (DVT) treatment
- DVT prevention
- Heart attack
Dosage forms
- Pill
- Pill
Price
Lowest price
$5.19
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$520.72
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Reviews
513 reviews so far
61%
saidit'sworth it
54%
saiditworked well
21%
saidit'sa big hassle
Have you used Coumadin (warfarin)?
Leave a review22 reviews so far
45%
saidit'sworth it
45%
saiditworked well
9%
saidit'sa big hassle
Have you used Xarelto (rivaroxaban)?
Leave a reviewSide effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
- Major bleeding needing transfusion4%
- Bleeding in the stomach & intestines2%
Risks and risk factors
- Life threatening bleeding
- Coumadin (warfarin) dose too high
- Age greater than 65 year
- History of stomach bleeding
- High blood pressure
- Kidney or liver problems
- Drug interactions
- Change in lifestyle or diet
- Alcohol use
- Certain genetic factors
- Harm to fetus
- Women of childbearing age
- Drug and diet interactions
- Potential surgery or amputation
- Blood clots and stroke
- Stopping Xarelto (rivaroxaban) too soon
- Artificial heart valve
- Blood clot in the spine
- Spinal puncture (spinal tap)
- Getting anesthesia in the spine (epidural anesthesia)
- Unusual bleeding
- History of bleeding problems
- Severe high blood pressure
- Age 65 or older
- Drug interactions
- Taking NSAIDs, aspirin, or other blood-thinning medicines
- Increased side effects
- Current kidney problems
- Current liver problems