Compare Losartan vs. Hyzaar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers blood pressure.

Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.

3.7/ 5 average rating with 535 reviewsforLosartan
Lowers blood pressure. Removes extra water from your body.

Hyzaar (Losartan / Hydrochlorothiazide) is a good combination blood pressure-lowering medicine to try if your blood pressure is very high.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Lowers the risk of heart attack and stroke.
  • A first-choice treatment for severe high blood pressure, combining the benefits of two blood pressure-lowering medicines with a single pill.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Helpful in getting rid of extra fluids if you have issues with fluid balance (like in congestive heart failure).
  • Most people have few side effects.
Downsides
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Will make you urinate more often.
  • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
  • Not safe to use if you're pregnant.
  • Needs dose adjustment if you have liver problems.
  • Your skin will be more sensitive to the sun while taking this.
  • Won't work as well if you have severe kidney problems.
  • Shouldn't take if you have a sulfa allergy.
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Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
535 reviews so far
57%
saidit'sworth it
48%
saiditworked well
16%
saidit'sa big hassle

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Side effects
4possible side effects
  • Upper respiratory infection
    8%
  • Dizziness
    3%
  • Back pain
    2%
  • Nasal congestion
    2%
See more detailed side effects
4possible side effects
  • Dizziness
    6%
  • Upper respiratory infection
    6%
  • Cough   
    3%
  • Back pain
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Liver damage
    • Concurrent liver disease
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
See more detailed risks and warnings
  • Harm to fetus
    • Women of childbearing age
  • Worsening kidney problems
    • History of kidney problems
  • Unusual tongue swelling
    • African descent
  • Heart or muscle problems due to potassium imbalance
    • Current kidney problems
    • Medicine that affects potassium
    • Use of salt substitute
  • Severe allergic reactions
    • History of sulfa allergies
  • Gout
    • History of gout
    • Current kidney problems
See more detailed risks and warnings