Compare Cresemba vs. Diflucan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Cresemba (isavuconazonium)

Prescription only

Diflucan (fluconazole)

Prescription only
Treats serious fungal infections.

Cresemba (isavuconazonium) is used to treat serious fungal infections as an alternative if you had problems with first choice medicines. However, it can be very expensive.

Treats yeast and other fungal infections.

Diflucan (fluconazole) is a cheap and effective treatment for fungal infections.

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3.9/ 5 average rating with 30 reviewsforDiflucan
Upsides
  • Unlike some other antifungal medications, you don’t need regular blood tests while you're taking Cresemba (isavuconazonium).
  • Cresemba (isavuconazonium) has fewer and milder side effects than other medicines for fungal infections.
  • You only need to take Cresemba (isavuconazonium) once a day after the first two days.
  • If you have conditions related to a slow or abnormal heartbeat, Cresemba (isavuconazonium) may be a good choice for treatment of a serious fungal infection.
  • Available in both an injectable form and capsules you take by mouth.
  • Available in a cheap generic version.
  • Single dose treatment for vaginal infections.
  • Available as a pill, liquid, or injection.
Downsides
  • Cresemba (isavuconazonium) needs to be taken twice daily.
  • Cresemba (isavuconazonium) may cause serious blood, muscle and liver problems.
  • Cresemba (isavuconazonium) is not recommended if you have kidney damage.
  • Cresemba (isavuconazonium) has a high incidence of side effects, including nausea, vomiting, loss of appetite, headache and malaise.
  • Cresemba (isavuconazonium) can negatively affect your cholesterol and blood sugar levels.
  • Excessive use of alcohol while on this medicine can harm your liver.
  • Can interfere with how other medicines work, especially birth control pills.
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Used for
  • Invasive aspergillosis
  • Invasive mucormycosis
Dosage forms
  • Pill
  • Injection
  • Pill
  • Liquid
  • Injection
Price
Lowest price
$304.01
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Lowest price
$4.00
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Reviews
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30 reviews so far
73%
saidit'sworth it
60%
saiditworked well
20%
saidit'sa big hassle

Have you used Diflucan (fluconazole)?

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Side effects
25possible side effects
  • Nausea
    28%
  • Vomiting
    25%
  • Diarrhea
    24%
  • Low potassium
    19%
  • Abdominal pain
    17%
  • Headache
    17%
  • Changes in liver blood tests
    17%
  • Trouble breathing
    17%
  • Swelling in the arms and legs
    15%
  • Constipation
    14%
  • Insomnia
    11%
  • Fatigue
    11%
  • Kidney failure
    10%
  • Back pain
    10%
  • Chest pain
    9%
  • Decreased appetite
    9%
  • Confusion/delirium
    9%
  • Skin rash
    9%
  • Itching
    8%
  • Low blood pressure
    8%
  • Anxiety
    8%
  • Acute respiratory failure
    7%
  • Indigestion
    6%
  • Injection site reactions
    6%
  • Low magnesium
    5%
See more detailed side effects
4possible side effects
  • Headache
    13%
  • Nausea
    7%
  • Abdominal pain
    6%
  • Diarrhea
    3%
See more detailed side effects
Risks and risk factors
  • Liver problems
  • Infusion problems
  • Severe allergic reactions
  • Risks to fetus
    • Pregnancy
  • Drug interactions
See more detailed risks and warnings
  • Liver disease
  • Serious immediate allergic reaction
  • Skin rash
  • Use in pregnancy
See more detailed risks and warnings
Learn more about Cresemba (isavuconazonium)
Learn more about Diflucan (fluconazole)