Compare Cresemba vs. Noxafil
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats serious fungal infections.
Cresemba (isavuconazonium) is used to treat serious fungal infections as an alternative if you had problems with first choice medicines. However, it can be very expensive.
Treats and prevents fungal infections.
Noxafil (posaconazole) works against many different fungal infections, but may require close follow-up for potential side effects and drug interactions.
Upsides
- Unlike some other antifungal medications, you don’t need regular blood tests while you're taking Cresemba (isavuconazonium).
- Cresemba (isavuconazonium) has fewer and milder side effects than other medicines for fungal infections.
- You only need to take Cresemba (isavuconazonium) once a day after the first two days.
- If you have conditions related to a slow or abnormal heartbeat, Cresemba (isavuconazonium) may be a good choice for treatment of a serious fungal infection.
- Available in both an injectable form and capsules you take by mouth.
- Noxafil (posaconazole) works against more types of fungal infections than other medications like it.
- Available in liquid form if you have difficulty swallowing pills.
Downsides
- Cresemba (isavuconazonium) needs to be taken twice daily.
- Cresemba (isavuconazonium) may cause serious blood, muscle and liver problems.
- Cresemba (isavuconazonium) is not recommended if you have kidney damage.
- Cresemba (isavuconazonium) has a high incidence of side effects, including nausea, vomiting, loss of appetite, headache and malaise.
- Cresemba (isavuconazonium) can negatively affect your cholesterol and blood sugar levels.
- Available as brand version only so may be more expensive than other medications like it.
- Noxafil (posaconazole) has many drug interactions.
- The pill and liquid forms are not readily interchangeable without your doctor's help.
Used for
- Invasive aspergillosis
- Invasive mucormycosis
- Prevention of fungal infection.
- Treatment of fungal infection in the mouth or throat
Dosage forms
- Pill
- Injection
- Extended release pill
- Liquid
Price
Lowest price
$5121.54
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$6092.22
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Side effects
25possible side effects
- Nausea28%
- Vomiting25%
- Diarrhea24%
- Low potassium19%
- Abdominal pain17%
- Headache17%
- Changes in liver blood tests17%
- Trouble breathing17%
- Swelling in the arms and legs15%
- Constipation14%
- Insomnia11%
- Fatigue11%
- Kidney failure10%
- Back pain10%
- Chest pain9%
- Decreased appetite9%
- Confusion/delirium9%
- Skin rash9%
- Itching8%
- Low blood pressure8%
- Anxiety8%
- Acute respiratory failure7%
- Indigestion6%
- Injection site reactions6%
- Low magnesium5%
16possible side effects
- Diarrhea10%
- Nausea9%
- Headache8%
- Vomiting7%
- Fever6%
- Abdominal pain5%
- Low white blood cells4%
- Fatigue3%
- Herpes simplex3%
- Lung infection3%
- Coughing3%
- Rash3%
- Anorexia2%
- Weakness2%
- Low red blood cells2%
- Increased sweating2%
Risks and risk factors
- Liver problems
- Infusion problems
- Severe allergic reactions
- Risks to fetus
- Pregnancy
- Drug interactions
- Abnormal heartbeat
- QT prolongation
- Arrhythmia
- Drugs that cause prolonged QT interval
- Abnormal electrolytes
- Liver problems
- Blood disorder
- Liver disease
- Kidney problems
- Kidney problems
- Kidney disease
- Drug toxicity