Compare cyclosporine vs. CellCept

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Neoral (cyclosporine)

Prescription only

CellCept (mycophenolate)

Prescription only
Suppresses the immune system.

Neoral (cyclosporine) is good at preventing rejection of a transplanted organ, and is also used for treating rheumatoid arthritis and psoriasis.

Prevents rejection of a transplanted organ.

CellCept (mycophenolate) is good at preventing organ transplant rejection, but you’ll need regular blood tests to make sure you don't develop any serious side effects.

Upsides
  • Neoral (cyclosporine) is safe for pregnant women to use.
  • Neoral (cyclosporine) does not affect blood sugar levels as much as others in the same drug class.
  • CellCept (mycophenolate) is a first-choice medication for preventing organ rejection since it doesn't hurt the kidneys or liver like its alternatives.
  • With CellCept (mycophenolate), you might be able to take a lower dose of your other anti-rejection medications.
Downsides
  • You'll need regular blood tests to make sure Neoral (cyclosporine) isn't affecting your body negatively.
  • Neoral (cyclosporine) can cause high blood pressure and kidney damage, especially with lifelong use.
  • You might need to take other medications to control your blood pressure while on Neoral (cyclosporine).
  • You might need to take other medications to control your blood pressure, blood sugar, or cholesterol while on CellCept (mycophenolate).
  • You can’t get certain vaccines while taking CellCept (mycophenolate).
  • You can’t breastfeed while on this medication.
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Used for
  • Prevention of heart transplant rejection
  • Prevention of kidney transplant rejection
  • Prevention of liver transplant rejection
  • Graft-versus-host disease
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
  • Suspension
Price
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Reviews
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Side effects
17possible side effects
  • High blood pressure
    53%
  • Abnormal kidney function
    38%
  • Tremor
    31%
  • Abnormal hair growth
    28%
  • Acne
    20%
  • Headache
    15%
  • Nausea/vomiting
    10%
  • Liver damage
    7%
  • Stomach discomfort
    7%
  • Low white blood cells
    6%
  • Blood cell tumor
    6%
  • Gum swelling
    5%
  • Uncontrolled shaking
    4%
  • Diarrhea
    4%
  • Swelling of breasts
    4%
  • Common cold symptoms
    3%
  • Burning or tingling in hands, arms, legs, or feet
    2%
See more detailed side effects
40possible side effects
  • High blood pressure
    78%
  • Swelling in arms and legs
    64%
  • Headache
    54%
  • Nausea
    54%
  • Fever
    47%
  • High blood sugar
    47%
  • Diarrhea
    45%
  • Lack of energy
    43%
  • Low red blood cells
    43%
  • High white blood cells
    41%
  • High cholesterol
    41%
  • Constipation
    41%
  • Trouble sleeping
    41%
  • Higher blood creatinine (marker of kidney function)
    39%
  • Lung infection
    37%
  • Shortness of breath
    37%
  • Back pain
    35%
  • Higher blood urea nitrogen (marker of kidney function)
    35%
  • Stomach pain
    34%
  • Vomiting
    34%
  • Low blood pressure
    33%
  • Low blood potassium
    32%
  • Increased cough
    31%
  • Low white blood cells
    30%
  • Lung problems
    30%
  • Dizziness
    28%
  • Anxiety
    28%
  • Swelling
    27%
  • Infection
    26%
  • Chest pain
    26%
  • Heart problems
    26%
  • Sinus inflammation
    26%
  • Low platelets
    24%
  • Tremor
    24%
  • Higher blood lactate dehydrogenase (marker of damaged cells)
    23%
  • Abnormal kidney function
    22%
  • Rash
    22%
  • Burning or tingling in hands, arms, legs, or feet
    21%
  • Fast heart rate
    20%
  • Very low neutrophil (type of white blood cell) count
    3%
See more detailed side effects
Risks and risk factors
  • Cancer
    • Taking Neoral (cyclosporine) for a long time
    • Prolonged exposure to sunlight
    • UV light
  • Serious infections
    • Taking other immunosuppressants
    • Age 60 or older
    • Weak immune system
  • High blood pressure
    • High blood pressure
    • Taking other medicines that can raise blood pressure
  • Kidney damage
    • Taking Neoral (cyclosporine) for a long time
    • Taking high doses of Neoral (cyclosporine)
    • Poor kidney function
    • Donor age 50 or older
    • Taking other medicines that can damage the kidneys
    • Taking medicines that interact with Neoral (cyclosporine)
  • Drug interactions
    • Taking multiple medicines
See more detailed risks and warnings
  • Harm to fetus
    • Sexually active women of childbearing age
  • Serious infections
    • Taking other immunosuppressants
    • Age 60 or older
    • Weak immune system
  • Blood disorders
  • Cancer
    • Taking CellCept (mycophenolate) for a long time
    • Prolonged exposure to sunlight
    • UV light
See more detailed risks and warnings