Compare Cymbalta vs. Remeron
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Improves mood and relieves certain types of pain.
Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of chronic pain, but it is more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.
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3.6/ 5 average rating with 496 reviewsforCymbalta
Improves mood.
Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.
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3.3/ 5 average rating with 152 reviewsforRemeron
Upsides
- Cymbalta (duloxetine) may help relieve nerve pain from diabetes and other forms of chronic pain.
- Cymbalta (duloxetine) has several uses, which may be good for people with multiple conditions.
- Available as a generic, which is cheaper.
- Effective at relieving some depression symptoms.
- Starts to work more quickly than most antidepressants.
- Can help you fall asleep if you have trouble sleeping.
- Can also help relieve anxiety.
- Good option if you are underweight or frail, because it can help you gain weight.
- Available as a generic.
Downsides
- Cymbalta (duloxetine) may not be a good option if you're a heavy drinker, or have liver or kidney problems.
- Cymbalta (duloxetine) can increase high blood pressure.
- Like most antidepressants, Cymbalta (duloxetine) can cause higher risk of suicidal thoughts and behavior for people aged 24 and younger.
- Makes you more tired than other antidepressants.
- More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Used for
- Depression
- Anxiety
- Diabetic neuropathy (nerve damage)
- Fibromyalgia
- Chronic muscle pain
- Urinary incontinence (women)
Dosage forms
- Pill
- Extended release
- Pill
- Dissolving tablet
Price
Lowest price
$10.70
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$8.84
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Reviews
496 reviews so far
58%
saidit'sworth it
49%
saiditworked well
24%
saidit'sa big hassle
Have you used Cymbalta (duloxetine)?
Leave a review152 reviews so far
45%
saidit'sworth it
39%
saiditworked well
26%
saidit'sa big hassle
Have you used Remeron (mirtazapine)?
Leave a reviewSide effects
12possible side effects
- Nausea23%
- Headache14%
- Dry mouth13%
- Drowsiness10%
- Fatigue9%
- Difficulty sleeping9%
- Constipation9%
- Dizziness9%
- Diarrhea9%
- Decreased appetite7%
- Excessive sweating6%
- Abdominal pain5%
17possible side effects
- Sleepiness54%
- Dry mouth25%
- Increased appetite17%
- Increased appetite17%
- Constipation13%
- Weight gain12%
- Lack of energy8%
- Dizziness7%
- Flu syndrome5%
- Abnormal dreams4%
- Abnormal thinking3%
- Back pain2%
- Swelling in limbs2%
- Muscle pain2%
- Tremor2%
- Confusion2%
- Urinary frequency2%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort
- Withdrawal
- Stopping Cymbalta (duloxetine) abruptly
- Increased bleeding
- Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)
- Changes in blood pressure and risk of falls
- Elderly patients
- History of gait disturbances
- Taking more than 60 mg of Cymbalta (duloxetine) daily
- Taking other medicines that lower blood pressure
- History of high blood pressure
- Bipolar disorder
- History of bipolar disorder
- At risk for bipolar disorder
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Using other medications that affect serotonin
- Heart problems
- History of heart problems
- History of liver problems
- Higher dose
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert
- Weight gain
- Blood disorders