Compare Dayquil Cold And Flu vs. Advil Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Relieves cold and flu symptoms.

Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a useful combination medicine that relieves cold and flu symptoms, but make sure you really need all of its ingredients.

3.7/ 5 average rating with 1034 reviewsforDayquil Cold And Flu
Relieves pain and congestion.

Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.

3.6/ 5 average rating with 1125 reviewsforAdvil Congestion Relief
Upsides
  • Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
1034 reviews so far
81%
saidit'sworth it
38%
saiditworked well
5%
saidit'sa big hassle

Have you used Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan)?

Leave a review
1125 reviews so far
73%
saidit'sworth it
32%
saiditworked well
7%
saidit'sa big hassle

Have you used Advil Congestion Relief (Ibuprofen / Phenylephrine)?

Leave a review
Side effects
The Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
The Advil Congestion Relief (Ibuprofen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver damage
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other Tylenol-containing medicines
    • History of liver disease
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Harm to fetus
    • Women of childbearing age
  • Chronic cough
    • History of chronic obstructive pulmonary disease (COPD)
    • History of smoking
See more detailed risks and warnings
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 60 years or older
    • Taking aspirin, NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
  • Harm to fetus
    • Women of childbearing age
  • High blood pressure
    • History of high blood pressure
  • Lower kidney function
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking high blood pressure medications
    • Age 65 years or older
  • Heart attack or stroke
    • History of heart problems
    • Age 65 years or older
    • Taking with aspirin
See more detailed risks and warnings