Compare Delsym vs. Nyquil Cold And Flu
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves coughing.
Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.
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3.3/ 5 average rating with 127 reviewsforDelsym
Relieves cold and flu symptoms, and helps you sleep.
Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a useful combination medicine that relieves cold and flu symptoms and will help you sleep. Make sure you really need all of its ingredients.
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3.8/ 5 average rating with 1188 reviewsforNyquil Cold And Flu
Upsides
- Good for treating dry cough.
- Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
- Available as a liquid and a tablet.
- Some products relieve cough for up to 12 hours.
- Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have watery eyes, a cough, fever, and pain.
- The cough medicine (dextromethorphan) works well and has very few side effects.
- The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
- The antihistamine (doxylamine) will help you sleep.
Downsides
- Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
- If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
- If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
- You shouldn't use it if you have high blood pressure.
- To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Used for
Dosage forms
- Pill
- Liquid extended release
- Pill
- Liquid
Price
Lowest price
$10.73
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$9.59
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Reviews
127 reviews so far
63%
saidit'sworth it
32%
saiditworked well
12%
saidit'sa big hassle
Have you used Delsym (Dextromethorphan)?
Leave a review1188 reviews so far
83%
saidit'sworth it
42%
saiditworked well
7%
saidit'sa big hassle
Have you used Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine)?
Leave a reviewSide effects
The Delsym (Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
The Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Serotonin syndrome
- Using other medications that affect serotonin
- Liver damage
- Drinking more than 2 alcoholic beverages a day
- Taking with other Tylenol-containing medicines
- History of liver disease
- Serotonin syndrome
- Using other medications that affect serotonin
- Driving impairment
- Taking with alcohol
- Taking with other medicines that make you less alert
- Antihistamine side effects
- Age 65 years or older
- Glaucoma
- Benign prostatic hypertrophy (BPH)