Compare Delsym vs. Phenylephrine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.
Sudafed Pe (Phenylephrine) is a good medication for relieving stuffy nose. It doesn't work as well as pseudoephedrine (Sudafed), but it has fewer side effects.
- Good for treating dry cough.
- Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
- Available as a liquid and a tablet.
- Some products relieve cough for up to 12 hours.
- Works to clear nasal congestion and helps you breathe better.
- Helpful in relieving congestion-related headaches.
- Has fewer side effects than other decongestants like pseudoephedrine.
- It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
- Doesn't give you rebound congestion (worse symptoms when you stop taking it) like nasal spray decongestants do.
- Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
- If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
- Phenylephrine doesn't last as long as other decongestants like pseudoephedrine (Sudafed).
- You shouldn't use it if you have high blood pressure.
- Can make your heart race or make you feel anxious and restless.
- Shouldn't use it before you want to sleep.
- Not as effective after using it for 4 days in a row.
- Liquid extended release
- Nasal spray
- Eye drops
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- Serotonin syndrome
- Using other medications that affect serotonin
- High blood pressure
- History of high blood pressure
- Taking MAO inhibitors
- Heart problems
- History of heart problems
- Age 65 years or older
- Harm to fetus
- Women of childbearing age