Compare Delzicol vs. Asacol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Delzicol (mesalamine)

Prescription only

Lialda (Mesalamine)

Prescription only
Treats ulcerative colitis and helps prevent flares.

Delzicol (mesalamine) effectively reduces symptoms of a flare for mild to moderate ulcerative colitis in both children and adults, but can cause burping and stomach discomfort.

Treats inflammatory bowel disease.

Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.

Upsides
  • Delzicol (mesalamine) effectively treats ulcerative colitis flares.
  • This drug is often used as the first-choice treatment in adults and children.
  • If you have trouble swallowing the drug whole, the pill can be opened and you can swallow the tablets inside.
  • Can be used in children 5 years and older.
  • Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
  • About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
  • Available in tablets, capsules, enemas, and suppositories.
  • Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
Downsides
  • Treatment dosage must be taken 3 times a day for a total of 6 weeks.
  • Can take a few weeks before you start to feel the effects.
  • Delzicol (mesalamine) is not available as a cheaper, generic form.
  • Combination therapy with oral and rectal forms may be needed for some people.
  • This form of mesalamine isn't used for maintenance, only to help reduce flare symptoms.
  • No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
  • Doesn't work well for severe colon inflammation.
  • You may need to take Lialda (Mesalamine) three or four times a day.
  • Not a good option if you have kidney disease.
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Used for
Dosage forms
  • Delayed-release pill
  • Pill
  • Extended release
  • Enema
  • Suppository
Price
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Reviews
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Side effects
9possible side effects
  • Burping
    26%
  • Abdominal pain
    21%
  • Constipation
    11%
  • Dizziness
    9%
  • Runny nose
    8%
  • Back pain
    6%
  • Rash
    6%
  • Upset stomach
    4%
  • Flu syndrome
    4%
See more detailed side effects
35possible side effects
  • Headache
    35%
  • Abdominal pain
    18%
  • Eructation
    16%
  • Pain
    14%
  • Nausea
    13%
  • Pharyngitis
    11%
  • Dizziness
    8%
  • Asthenia
    7%
  • Diarrhea
    7%
  • Back pain
    7%
  • Fever
    6%
  • Rash
    6%
  • Dyspepsia
    6%
  • Rhinitis
    5%
  • Arthralgia
    5%
  • Hypertonia
    5%
  • Vomiting
    5%
  • Constipation
    5%
  • Flatulence
    3%
  • Dysmenorrhea
    3%
  • Chest pain
    3%
  • Chills
    3%
  • Flu syndrome
    3%
  • Peripheral edema
    3%
  • Myalgia
    3%
  • Sweating
    3%
  • Colitis exacerbation
    3%
  • Pruritus
    3%
  • Adverse events
    3%
  • Acne
    2%
  • Increased cough
    2%
  • Malaise
    2%
  • Arthritis
    2%
  • Conjunctivitis
    2%
  • Insomnia
    2%
See more detailed side effects
Risks and risk factors
  • Kidney problems
    • Preexisting kidney problems
    • Taking medications toxic to the kidney
  • Liver problems
    • Preexisting liver problems
    • Taking other medications toxic to the liver
  • Serious allergic reactions
    • Sulfasalazine reaction
  • Abnormal response to Delzicol (mesalamine)
See more detailed risks and warnings
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Serious allergic reactions
    • Phenylketonuria (PKU)
  • Worsening kidney or liver function
    • Kidney problems
    • Liver problems
  • Blood disorders
    • Age 65 or older
  • Liver toxicity
    • Liver problems
  • Worsening of colitis
    • Taking Lialda (Mesalamine) at the start of treatment
See more detailed risks and warnings