Compare Depakote vs. Myrbetriq

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Depakote (divalproex)

Prescription only

Myrbetriq (mirabegron)

Prescription only
Treats and prevents seizures, and stabilizes mood.

Depakote (divalproex) is good for long-term prevention of seizures, manic episodes in bipolar disorder, and migraines.

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3.3/ 5 average rating with 97 reviewsforDepakote
Treats overactive bladder.

Myrbetriq (mirabegron) is a good treatment for overactive bladder with the least chance for dry mouth and constipation, but talk to your doctor if you have high blood pressure.

Upsides
  • Lowers the frequency of seizures, especially for people with absence seizures or complex partial seizures.
  • Depakote (divalproex) is a first-line treatment to stabilize mood for people with bipolar disorder.
  • Depakote (divalproex) is helpful for preventing frequent migraines.
  • The sprinkle pill can be swallowed whole or can be opened up and mixed with applesauce if you have a hard time swallowing.
  • Depakote (divalproex) is available as a generic.
  • Myrbetriq (mirabegron) helps you to have better control over your urination.
  • Myrbetriq (mirabegron) causes less drowsiness and constipation than other medicines for overactive bladder.
  • May be used if you have glaucoma.
  • Myrbetriq (mirabegron) may be safer to use if you are over 65 years old.
Downsides
  • It can take 3 to 4 weeks before you feel the full effects of Depakote (divalproex).
  • Depakote (divalproex) is not a good medication for people with liver problems.
  • Requires regular blood tests to see how the medication is affecting your body.
  • Depakote (divalproex) can make you bleed more easily.
  • Myrbetriq (mirabegron) might raise your blood pressure.
  • If you have an obstruction in your bladder, Myrbetriq (mirabegron) might make you retain more urine.
  • Myrbetriq (mirabegron) may be very expensive depending on your insurance.
  • Not recommended if you have severe liver or kidney disease.
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Used for
Dosage forms
  • Pill
  • Extended release pill
  • Delayed release pill
  • Extended release
Price
Lowest price
$20.61
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Lowest price
$400.23
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Reviews
97 reviews so far
46%
saidit'sworth it
40%
saiditworked well
27%
saidit'sa big hassle

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Side effects
9possible side effects
  • Nausea
    22%
  • Sleepiness
    19%
  • Dizziness
    12%
  • Vomiting
    12%
  • Accidental injury
    11%
  • Feeling weak
    10%
  • Abdominal pain
    9%
  • Upset stomach
    9%
  • Rash
    6%
See more detailed side effects
8possible side effects
  • High blood pressure
    11%
  • Common cold symptoms
    4%
  • Urinary tract infection
    4%
  • Headache
    2%
  • Constipation
    2%
  • Chest cold infection
    2%
  • Joint pain
    2%
  • Rapid heart beat
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
  • Liver damage
    • Children under age 2
    • History of metabolic disorders
    • Severe seizure disorder
    • Brain disease
    • History of liver problems
  • Pancreas problems
  • Suicidal thoughts or behavior
    • History of depression
  • Increased bleeding
  • Mental changes
    • History of metabolic disorders
    • People also taking Topamax
See more detailed risks and warnings
  • Increased blood pressure
    • Untreated high blood pressure
  • Urinary retention
    • Bladder outlet obstruction
  • Unusual swelling
See more detailed risks and warnings
Learn more about Depakote (divalproex)
Learn more about Myrbetriq (mirabegron)