Compare Depo-Testosterone vs. Androderm

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats low testosterone.

This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.

3.0/ 5 average rating with 100 reviewsforDepo-Testosterone
Treats low testosterone.

The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.

  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
  • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
  • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
  • The testosterone patch only has to be placed once each night.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
  • Not available in generic.
  • You have to be careful to rotate the testosterone patch to a different part of your body each night.
  • Can cause skin irritation.
  • Has to be removed before you have an MRI.
  • The patch can become loose if you do heavy exercise or sweat a lot.
Used for
  • Low testosterone
  • Gender identity disorder (female-to-male transsexual)
  • Low testosterone
  • Male osteoporosis
  • Weight gain
Dosage forms
  • Injection
  • Patch
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
100 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Depo-Testosterone (Testosterone Cypionate Injection)?

Leave a review
Not enough review data.Leave a review
Side effects
The Depo-Testosterone (Testosterone Cypionate Injection) FDA package insert doesn’t have numbers about how common side effects are.
15possible side effects
  • Any appication site reaction
  • Application site pruritus
  • Application site vesicles
  • Back pain
  • Application site erythema
  • Application site exfoliation
  • Chills
  • Diarrhea
  • Fatigue
  • Gastroesophageal reflux disease
  • Hemarthrosis
  • Hematuria
  • Headache
  • Polyuria
  • Prostatitis
See more detailed side effects
Risks and risk factors
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • High calcium in the blood
    • Inability to move
    • Cancer
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings
No information currently available