Compare Detrol vs. Sanctura

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Detrol (tolterodine)

Prescription only

Sanctura (trospium)

Prescription only
Treats overactive bladder.

Detrol (tolterodine) is a good treatment for overactive bladder after exercises and other methods to control it haven't worked.

Treats overactive bladder.

Sanctura (trospium) is a good treatment for overactive bladder after exercises when other methods to control it haven't worked.

Upsides
  • Detrol (tolterodine) is effective at treating overactive bladder by lowering the urge to urinate, and controlling urination.
  • The tablet is available as a generic in both extended and immediate release, so you can take it once or twice a day.
  • Sanctura (trospium) is effective at treating overactive bladder.
  • Sanctura (trospium) may be a better choice if you have liver problems.
  • Sanctura (trospium) is available as a generic.
Downsides
  • Detrol (tolterodine) can cause drowsiness, dizziness and can increase your risk for falls.
  • Detrol (tolterodine) can cause severe dry mouth and eyes and constipation.
  • Generally not recommended if you are 65 or older.
  • Do not use if you have uncontrolled narrow-angle glaucoma.
  • You have to take Sanctura (trospium) on an empty stomach.
  • You may need to take Sanctura (trospium) twice a day.
  • Sanctura (trospium) can cause drowsiness, dizziness, and increase your risk for falls.
  • Generally not recommended if you older than 65.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
Price
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Reviews
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Side effects
10possible side effects
  • Dry mouth
    23%
  • Headache
    6%
  • Constipation
    6%
  • Stomach pain
    4%
  • Indigestion
    3%
  • Dry eyes
    3%
  • Sleepiness
    3%
  • Tiredness
    2%
  • Dizziness
    2%
  • Flu-like symptoms
    2%
See more detailed side effects
4possible side effects
  • Dry mouth
    11%
  • Constipation
    9%
  • Dry eyes
    2%
  • Gas
    2%
See more detailed side effects
Risks and risk factors
  • Face, lips, neck or throat swelling
  • Dizziness and drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Trouble urinating & stomach problems
    • History of bladder problems
    • History of stomach or intestine problems
  • Heartbeat problems
    • History of heartbeat problems
    • Taking medicines to conrol heartbeat
  • Liver and Kidney problems
    • History of liver problems
    • History of Kidney problems
See more detailed risks and warnings
  • Facial swelling & breathing problems
  • Difficulty concentrating
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary retention
    • Bladder outflow obstruction
  • Increased side effects
    • History of kidney problems
    • People age 65 or older
  • Heat exhaustion
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • People age 65 and older
See more detailed risks and warnings