Compare dexamethasone vs. Cimzia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Decadron (dexamethasone)

Prescription only

Cimzia (certolizumab)

Prescription only
Calms down your immune system.

Decadron (dexamethasone) is a long-acting oral corticosteroid that is very effective in treating allergic reactions and immune conditions, however, if you're taking Decadron (dexamethasone) for a long time, there can be serious side effects.

Calms the immune system and prevents joint damage.

Cimzia (certolizumab) effectively calms down your immune system, but you have to be comfortable receiving injections.

Upsides
  • Effective in treating many conditions.
  • Can improve energy and appetite.
  • Can control immune responses that are causing you discomfort and works quickly to relieve symptoms like swelling, rash, asthma attacks, and pain.
  • Has long-term benefit in calming down the immune system and keeping it from causing your body harm, such as in autoimmune conditions.
  • Available in generic form.
  • People taking Cimzia (certolizumab) for Crohn's disease, rheumatoid arthritis and other autoimmune conditions had greater clinical response compared to people who did not take Cimzia (certolizumab).
  • Compared to some other drugs used to treat autoimmune conditions, Cimzia (certolizumab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
  • You can give yourself Cimzia (certolizumab) on your own at home rather than visiting a clinic or hospital.
  • After the initial dosing, you need to take Cimzia (certolizumab) every 4 weeks.
  • Cimzia (certolizumab) has been on the market for almost 10 years.
Downsides
  • Many side effects, particularly with long term use.
  • Side effects include mood changes, trouble sleeping and increase in blood pressure and blood sugar at higher doses.
  • Long-term use can cause problems with skin, bone, eye health and put you at a higher risk for infections.
  • If you've been using corticosteroids for more than 2 weeks, you will need to work with a doctor to get off the medicine slowly.
  • Limited studies conducted with use of steroids during pregnancy or breastfeeding - potential harm to unborn baby.
  • Cimzia (certolizumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, or had tuberculosis (TB) in the past.
  • Can in some cases cause bladder infections, rash and respiratory infections (cold or flu)
  • In rare cases, Cimzia (certolizumab) has been associated with cancers in children and adolescents.
  • Can increase your risk of side effects if you have a history of heart failure, nervous system conditions, or hepatitis B.
  • There's no generic available and it can be expensive.
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Used for
  • Allergies
  • Skin Conditions
  • Endocrine Conditions
  • Eye Conditions
  • Stomach Conditions
  • Respiratory disorder
  • Multiple sclerosis flare
  • Hematologic Conditions
  • Cancer
  • Autoimmune and Rheumatic Conditions
  • Immune thrombocytopenia
  • Acute mountain sickness
  • Multiple myeloma
  • Prevention of nausea and vomiting from chemotherapy
Dosage forms
  • Pill
  • Liquid
  • Injection
Price
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Reviews
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Side effects
The Decadron (dexamethasone) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Infections
    38%
  • Upper airway infections
    20%
  • Urinary tract infections
    7%
  • Joint pain
    6%
See more detailed side effects
Risks and risk factors
  • Lowered adrenal function
    • Lowering dose or stopping too quickly especially after long-term treatment
    • Stress such as trauma, surgery or infection
  • Increased risk for infections
    • Taking other immunosuppressants
    • Long-term treatment
    • Not vaccinated against viral diseases
    • Contact with people who have viral illness
    • History of bacterial or viral conditions
  • Changes in heart and kidney function
    • Recent heart attack
  • Stomach and intestinal problems
    • History of stomach bleeding
    • Active or history of stomach ulcers
    • Ulcerative colitis
    • Taking Decadron (dexamethasone) with other medicine that can cause stomach problems
  • Bone effects
    • Dose of Decadron (dexamethasone)
    • Duration of treatment
  • Eye problems
See more detailed risks and warnings
  • Serious infections
    • Taking other immunosuppressant medications such as methotrexate or steroids
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities
  • Cancers
    • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Cimzia (certolizumab)
    • History of malignancy
    • Adolescent age
  • Heart problems
    • History of heart failure
  • Serious allergic reactions
  • Lower blood cell counts
  • Nervous system effects
    • Multiple sclerosis
    • Guillain-Barre syndrome
See more detailed risks and warnings