Compare Dexedrine vs. Adderall

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats attention deficit disorder.

Dexedrine (dextroamphetamine) is an effective medicine for treatment of ADHD, but often abused for recreational purposes.

4.3/ 5 average rating with 28 reviewsforDexedrine
Helps you focus and stay alert.

Adderall (dextroamphetamine / amphetamine) is a first-choice treatment for ADHD that's available as a generic, but it's a stimulant that can cause difficulty sleeping and other side effects.

3.9/ 5 average rating with 1309 reviewsforAdderall
  • Recommended as a first-choice treatment of ADHD.
  • Available as generic version.
  • For more flexible dosing schedule, Dexedrine (dextroamphetamine) is available in short and long formulations.
  • If you have difficulty swallowing pills, Dexedrine (dextroamphetamine) is available as a liquid.
  • First-choice medication to treat ADHD.
  • Adderall (dextroamphetamine / amphetamine) is used together with counseling or other non-drug therapies to treat ADHD.
  • Available as an affordable generic medication.
  • Available in both immediate and extended release forms.
  • For the extended release capsule, if you can't swallow the whole capsule, the capsule can be opened, mixed in a spoonful of applesauce, and swallowed.
  • Taking Dexedrine (dextroamphetamine) can decrease your appetite.
  • If taken late in the day, Dexedrine (dextroamphetamine) can cause insomnia.
  • People who take high doses of Dexedrine (dextroamphetamine) are more likely to have anxiety, restlessness, or irritability.
  • Requires a new prescription from your doctor every month.
  • Not a good option if you have a history of seizures.
  • Can be habit-forming so make sure you use it only as prescribed.
  • Must take in the morning and early afternoon, otherwise it can cause difficulty sleeping.
  • It's a controlled medication and should be locked up to prevent potential abuse.
  • Not safe for people with a history of heart problems.
  • For school-aged children, a second dose will likely need to be given at school.
Used for
Dosage forms
  • Pill
  • Extended release
  • Liquid
  • Pill
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28 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Dexedrine (dextroamphetamine)?

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1309 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Adderall (dextroamphetamine / amphetamine)?

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Side effects
The Dexedrine (dextroamphetamine) FDA package insert doesn’t have numbers about how common side effects are.
The Adderall (dextroamphetamine / amphetamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Abuse and dependence
    • History of drug abuse
  • Serious or life-threatening heart problems
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar disorder
  • Long-term growth suppression
    • Children
  • Seizures
    • History of seizures
  • Serotonin Syndrome (rare, life-threatening)
    • Using other medicines that increase serotonin levels in the brain
See more detailed risks and warnings
  • Serious or life-threatening cardiovascular events
    • History of heart problems
    • Misuse of Adderall (dextroamphetamine / amphetamine)
  • Dependence and abuse
    • History of drug abuse
    • Misuse of Adderall (dextroamphetamine / amphetamine)
  • Serotonin syndrome
    • Taking other medicines that affect serotonin levels
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar disorder
  • Driving impairment
    • Taking Adderall (dextroamphetamine / amphetamine) with alcohol
    • Taking other medicines that cause dizziness and/or drowsiness
  • Long-term growth suppression
    • Children ages 7 to 10
See more detailed risks and warnings