Compare Dexilant vs. Aciphex
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats heartburn.
Dexilant (dexlansoprazole) is an effective medicine to treat heartburn, but can be expensive since it is only available as a brand.
●●●●●
4.7/ 5 average rating with 73 reviewsforDexilant
Treats heartburn and ulcers.
Aciphex (rabeprazole) is good for treating heartburn and ulcers, but should not be used long-term.
Upsides
- Relieves heartburn symptoms better than other stomach medicines (like Pepcid, Tagamet, and Zantac).
- Lasts longer than other alternative stomach medicines.
- Convenient once daily dosing.
- Treats GERD in children 12 to 17 years of age.
- Can be swallowed whole, or contents of the pill can be emptied into applesauce for easy swallowing.
- Aciphex (rabeprazole) works better than over-the-counter medications that have not relieved your acid reflux.
- The delayed-release pill provides relief over 24 hours.
- Aciphex (rabeprazole) can be taken with or without food.
- The capsule can be safely used by children as young as 1 year old.
Downsides
- Similar to other proton pump inhibitors, Dexilant (dexlansoprazole) can weaken bones when taken for a long period of time.
- Can take a few days before you start to feel the full effects.
- Dexilant (dexlansoprazole) can affect how other medicines, vitamins, and minerals get absorbed in your body.
- There's no generic version available, so it can be expensive.
- Using Aciphex (rabeprazole) for a long time can can weaken your bones or increase your risk for infectious diarrhea.
- Lowers magnesium and vitamin B12 in your body so you may need to take supplements.
- Aciphex (rabeprazole) interferes with how many medications work.
Used for
- Acid Reflux
- Stomach ulcers
Dosage forms
- Delayed-release pill
- Dissolving tablet
- Delayed release pill
Price
Lowest price
$208.68
Find instant savings near youLowest price
$14.75
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
73 reviews so far
93%
saidit'sworth it
92%
saiditworked well
14%
saidit'sa big hassle
Have you used Dexilant (dexlansoprazole)?
Leave a reviewNot enough review data.Leave a review
Side effects
6possible side effects
- Diarrhea5%
- Abdominal pain4%
- Nausea3%
- Upper airway infection3%
- Gas3%
- Vomiting2%
5possible side effects
- Headache10%
- Diarrhea5%
- Nausea5%
- Vomiting4%
- Abdominal pain4%
Risks and risk factors
- Possible stomach cancer
- Kidney inflammation
- Severe diarrhea
- Being hospitalized
- Antibiotic use
- Bone fractures
- High dose Dexilant (dexlansoprazole)
- Long-term treatment with Dexilant (dexlansoprazole) (more than 1 year)
- Low bone mineral density
- Aged 50 years or older
- Alcohol
- Smoking
- Taking steroids or seizure medicines
- Low magnesium and vitamin B12 levels
- Taking digoxin or diuretics
- Lupus
- Stomach cancer
- Kidney inflammation
- Severe diarrhea
- Being hospitalized
- Antibiotic use
- Bone fractures
- High dose Aciphex (rabeprazole)
- Taking Aciphex (rabeprazole) for longer than one year
- Low bone mineral density
- Age 50 years or older
- Alcohol
- Smoking
- Taking steroids or anti-seizure medicines
- Low levels of magnesium and vitamin B12
- Lupus