Compare Dexilant vs. Alka-Seltzer

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats heartburn.

Dexilant (dexlansoprazole) is an effective medicine to treat heartburn, but can be expensive since it is only available as a brand.

4.7/ 5 average rating with 73 reviewsforDexilant
Relieves symptoms of indigestion and pain

Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) provides quick relief for heartburn, upset stomach, headaches, and general pain. However, you have to take it a few times a day to continue getting relief of your symptoms.

3.9/ 5 average rating with 1055 reviewsforAlka-Seltzer
Upsides
  • Relieves heartburn symptoms better than other stomach medicines (like Pepcid, Tagamet, and Zantac).
  • Lasts longer than other alternative stomach medicines.
  • Convenient once daily dosing.
  • Treats GERD in children 12 to 17 years of age.
  • Can be swallowed whole, or contents of the pill can be emptied into applesauce for easy swallowing.
  • Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) is a great option if you have an upset stomach and a headache or body aches at the same time.
  • Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) works quickly to relieve symptoms.
  • Available over the counter without a prescription.
  • Also, available as generic and is fairly cheap.
Downsides
  • Similar to other proton pump inhibitors, Dexilant (dexlansoprazole) can weaken bones when taken for a long period of time.
  • Can take a few days before you start to feel the full effects.
  • Dexilant (dexlansoprazole) can affect how other medicines, vitamins, and minerals get absorbed in your body.
  • There's no generic version available, so it can be expensive.
  • The effects of this medication don't last very long. Other medicines, like Zantac (H2 blockers) and omeprazole (proton pump inhibitors), work better and last longer.
  • Because this medicine contains aspirin, it raises the risk of bleeding, especially if you take any other blood thinning medicines.
  • People who are allergic to aspirin can't use this medication.
  • May not like the taste or fizz.
  • Kids or teenagers should not use Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) unless instructed by a doctor.
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Used for
Dosage forms
  • Delayed-release pill
  • Dissolving tablet
  • Effervescent tablet
Price
No pricing information available
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Reviews
73 reviews so far
93%
saidit'sworth it
92%
saiditworked well
14%
saidit'sa big hassle

Have you used Dexilant (dexlansoprazole)?

Leave a review
1055 reviews so far
81%
saidit'sworth it
52%
saiditworked well
8%
saidit'sa big hassle

Have you used Alka-Seltzer (aspirin / citric acid / sodium bicarbonate)?

Leave a review
Side effects
6possible side effects
  • Diarrhea
    5%
  • Abdominal pain
    4%
  • Nausea
    3%
  • Upper airway infection
    3%
  • Gas
    3%
  • Vomiting
    2%
See more detailed side effects
The Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Possible stomach cancer
  • Kidney inflammation
  • Severe diarrhea
    • Being hospitalized
    • Antibiotic use
  • Bone fractures
    • High dose Dexilant (dexlansoprazole)
    • Long-term treatment with Dexilant (dexlansoprazole) (more than 1 year)
    • Low bone mineral density
    • Aged 50 years or older
    • Alcohol
    • Smoking
    • Taking steroids or seizure medicines
  • Low magnesium and vitamin B12 levels
    • Taking digoxin or diuretics
  • Lupus
See more detailed risks and warnings
  • Taking the wrong medication
    • Not reading the drug label
  • Brain damage or death from Reye's Syndrome
    • Children 18 years or younger recovering from viral infections
  • High blood sodium levels
    • Current kidney disease
    • Dialysis
    • Age 65 or older
    • Hyperparathyroidism
    • Use of other medicines that can cause kidney damage
  • May worsen heart or kidney problems
    • Congestive heart failure (CHF)
    • High blood pressure
    • Current kidney disease
    • Kidney dialysis
  • Stomach Bleeding
    • History of stomach bleeding or ulcers
    • Age 60 or older
    • Also taking other blood thinners
    • Drinking 3 or more alcoholic drinks a day
  • Harm to unborn babies
    • Pregnancy
See more detailed risks and warnings