Compare Dexilant vs. Prevacid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Prevacid (lansoprazole)

Prescription or OTC
Treats heartburn.

Dexilant (dexlansoprazole) is an effective medicine to treat heartburn, but can be expensive since it is only available as a brand.

4.7/ 5 average rating with 73 reviewsforDexilant
Treats heartburn and stomach ulcers.

Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.

4.0/ 5 average rating with 21 reviewsforPrevacid
Upsides
  • Relieves heartburn symptoms better than other stomach medicines (like Pepcid, Tagamet, and Zantac).
  • Lasts longer than other alternative stomach medicines.
  • Convenient once daily dosing.
  • Treats GERD in children 12 to 17 years of age.
  • Can be swallowed whole, or contents of the pill can be emptied into applesauce for easy swallowing.
  • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
  • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
  • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
Downsides
  • Similar to other proton pump inhibitors, Dexilant (dexlansoprazole) can weaken bones when taken for a long period of time.
  • Can take a few days before you start to feel the full effects.
  • Dexilant (dexlansoprazole) can affect how other medicines, vitamins, and minerals get absorbed in your body.
  • There's no generic version available, so it can be expensive.
  • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
  • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
  • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
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Used for
Dosage forms
  • Delayed-release pill
  • Dissolving tablet
  • Extended release
  • Dissolving tablet extended release
  • Liquid
Price
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Reviews
73 reviews so far
93%
saidit'sworth it
92%
saiditworked well
14%
saidit'sa big hassle

Have you used Dexilant (dexlansoprazole)?

Leave a review
21 reviews so far
71%
saidit'sworth it
71%
saiditworked well
19%
saidit'sa big hassle

Have you used Prevacid (lansoprazole)?

Leave a review
Side effects
6possible side effects
  • Diarrhea
    5%
  • Abdominal pain
    4%
  • Nausea
    3%
  • Upper airway infection
    3%
  • Gas
    3%
  • Vomiting
    2%
See more detailed side effects
2possible side effects
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
Risks and risk factors
  • Possible stomach cancer
  • Kidney inflammation
  • Severe diarrhea
    • Being hospitalized
    • Antibiotic use
  • Bone fractures
    • High dose Dexilant (dexlansoprazole)
    • Long-term treatment with Dexilant (dexlansoprazole) (more than 1 year)
    • Low bone mineral density
    • Aged 50 years or older
    • Alcohol
    • Smoking
    • Taking steroids or seizure medicines
  • Low magnesium and vitamin B12 levels
    • Taking digoxin or diuretics
  • Lupus
See more detailed risks and warnings
  • Stomach cancer
  • Acute kidney damage
  • Clostridium difficile associated diarrhea (CDAD)
  • Bone fractures
    • High dose Prevacid (lansoprazole)
    • Long-term treatment with Prevacid (lansoprazole)
    • Low bone mineral density
    • Older age
  • Lupus
  • Low vitamin or mineral levels
See more detailed risks and warnings