Compare Dificid vs. Biaxin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Dificid (fidaxomicin)

Prescription only

Biaxin (clarithromycin)

Prescription only
Treats diarrhea caused by C. diff infection.

Dificid (fidaxomicin) works well to treat a severe gut infection caused by the bacterium Clostridium difficile.

Treats bacterial infections.

Biaxin (clarithromycin) is a good first-choice medicine to treat most common respiratory infections. Side-effects are common, but mild.

Upsides
  • You only have to take it twice daily, regardless of meal time. You can take it together with other medications. It has minimal side effects.
  • Good first-choice treatment for respiratory infections.
  • Compared to similar medicines, Biaxin (clarithromycin) is better tolerated.
  • Available as an extended-release pill for convenient once daily dosing and as a liquid for trouble swallowing pills.
  • Children as young as 6 months can use Biaxin (clarithromycin) safely and effectively.
Downsides
  • Dificid (fidaxomicin) is comparatively effective, but costs more than alternatives.
  • Can cause changes in taste.
  • Can cause abnormal heart rhythms.
  • Biaxin (clarithromycin), can interact with other medications. Talk to your doctor or pharmacist, especially if you are taking medicines for heart problems or gout.
  • If you have kidney or liver problems, Biaxin (clarithromycin) might not be a good option.
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Dosage forms
  • Pill
  • Pill
  • Extended release pill
  • Liquid
Price
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Reviews
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Side effects
5possible side effects
  • Nausea
    11%
  • Vomiting
    7%
  • Abdominal pain
    6%
  • Bleeding in the gut
    4%
  • Low blood counts
    2%
See more detailed side effects
7possible side effects
  • Nausea
    12%
  • Vomiting
    8%
  • Abnormal changes in taste
    4%
  • Abdominal pain
    3%
  • Diarrhea
    3%
  • Rash
    3%
  • Headache
    2%
See more detailed side effects
Risks and risk factors
  • Appropriate use
  • Serious immediate allergic reaction
  • Cross allergies
    • Macrolide Antibiotic Allergy
See more detailed risks and warnings
  • Serious allergic reaction
  • Abnormal heart rhythm
    • History of heart arrhythmias
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
    • Elderly
  • Liver toxicity
  • Serious drug interactions
  • Severe diarrhea caused by bacteria
    • Antibiotic use
  • Birth defects
    • Pregnancy
See more detailed risks and warnings