Compare Diflucan vs. Noxafil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Diflucan (fluconazole)

Prescription only

Noxafil (posaconazole)

Prescription only
Treats yeast and other fungal infections.

Diflucan (fluconazole) is a cheap and effective treatment for fungal infections.

3.9/ 5 average rating with 30 reviewsforDiflucan
Treats and prevents fungal infections.

Noxafil (posaconazole) works against many different fungal infections, but may require close follow-up for potential side effects and drug interactions.

Upsides
  • Available in a cheap generic version.
  • Single dose treatment for vaginal infections.
  • Available as a pill, liquid, or injection.
  • Noxafil (posaconazole) works against more types of fungal infections than other medications like it.
  • Available in liquid form if you have difficulty swallowing pills.
Downsides
  • Excessive use of alcohol while on this medicine can harm your liver.
  • Can interfere with how other medicines work, especially birth control pills.
  • Available as brand version only so may be more expensive than other medications like it.
  • Noxafil (posaconazole) has many drug interactions.
  • The pill and liquid forms are not readily interchangeable without your doctor's help.
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Used for
  • Prevention of fungal infection.
  • Treatment of fungal infection in the mouth or throat
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Extended release pill
  • Liquid
Price
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Reviews
30 reviews so far
73%
saidit'sworth it
60%
saiditworked well
20%
saidit'sa big hassle

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Side effects
4possible side effects
  • Headache
    13%
  • Nausea
    7%
  • Abdominal pain
    6%
  • Diarrhea
    3%
See more detailed side effects
16possible side effects
  • Diarrhea
    10%
  • Nausea
    9%
  • Headache
    8%
  • Vomiting
    7%
  • Fever
    6%
  • Abdominal pain
    5%
  • Low white blood cells
    4%
  • Fatigue
    3%
  • Herpes simplex
    3%
  • Lung infection
    3%
  • Coughing
    3%
  • Rash
    3%
  • Anorexia
    2%
  • Weakness
    2%
  • Low red blood cells
    2%
  • Increased sweating
    2%
See more detailed side effects
Risks and risk factors
  • Liver disease
  • Serious immediate allergic reaction
  • Skin rash
  • Use in pregnancy
See more detailed risks and warnings
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
  • Liver problems
    • Blood disorder
    • Liver disease
  • Kidney problems
    • Kidney problems
    • Kidney disease
  • Drug toxicity
See more detailed risks and warnings