Compare Dilantin vs. Topamax
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats and prevents seizures.
Dilantin (phenytoin) is very good at treating and preventing seizures, but it has many drug interactions and some serious side effects.
Prevents seizures and migraine headaches.
Topamax (topiramate) is very effective at preventing many types of seizures and migraines, but it can cause several severe side effects that can lead to stopping the medication.
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3.3/ 5 average rating with 56 reviewsforTopamax
Upsides
- If you have trouble swallowing pills, Dilantin (phenytoin) is available as a chewable tablet or a liquid.
- Dilantin (phenytoin) is available in a cheaper, generic form.
- Can lower your number of seizures and also prevent migraine headaches. This medicine can be used on its own or with other antiepileptic medicines to lower the frequency of seizures.
- Doesn't need routine blood tests like similar medications.
- Available in short-acting and long-acting forms.
- Comes as a generic, so it's relatively cheap.
Downsides
- Need to get regular blood tests while taking Dilantin (phenytoin) to make sure the medicine level is safe and effective in your body.
- Can cause changes in your appearance, such as unwanted hair growth and enlargement of your gums.
- If you have kidney problems, you’ll need regular blood tests to check your kidney function and to make sure Dilantin (phenytoin) levels in your blood don’t get too high.
- Dilantin (phenytoin) can make other medications not work as well, including birth control.
- Can cause many severe side effects. People starting Topamax (topiramate) need to be monitored for these effects as soon as they start treatment.
- This medicine can take 4 to 6 weeks for the full effects of this medication to kick in, especially for people taking it for migraines.
- Children taking Topamax (topiramate) for long periods of time need to have their dose adjusted by their pediatrician as they grow.
- At higher doses (ie. 400 mg/day), children may experience difficulty with concentration/attention, fever, flushing, and confusion.
Used for
- Generalized seizure
- Tonic-clonic seizure
- Complex partial seizure
- Seizure (during and following neurosurgery)
- Seizure in pregnant woman
- Pressure ulcer
- Wound healing
- Seizures
- Migraine prevention
- Alcoholism
- Essential tremors
- Eating disorder
Dosage forms
- Extended release
- Chewable tablet
- Liquid
- Pill
- Extended release capsule
Price
Lowest price
$69.99
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$51.38
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Reviews
Not enough review data.Leave a review
56 reviews so far
52%
saidit'sworth it
50%
saiditworked well
36%
saidit'sa big hassle
Have you used Topamax (topiramate)?
Leave a reviewSide effects
The Dilantin (phenytoin) FDA package insert doesn’t have numbers about how common side effects are.
39possible side effects
- Sleepiness26%
- Loss of appetite24%
- Fatigue16%
- Injury14%
- Nervousness14%
- Personality disorder (behavior problems)11%
- Difficulty with concentration/attention10%
- Weight loss9%
- Aggressive reaction9%
- Abnormal gait8%
- Purpura8%
- Difficulty sleeping8%
- Viral infection7%
- Impaired coordination6%
- Nausea6%
- Increased saliva6%
- Muscle spasm5%
- Constipation5%
- Difficulty with memory5%
- Pneumonia5%
- Dizziness4%
- Speech disorders/ related speech problems4%
- Nose bleed4%
- Confusion4%
- Urinary incontinence4%
- Stomach flu3%
- Psychomotor slowing3%
- Skin disorder3%
- Allergic reaction2%
- Abnormal reflexes2%
- Thirst2%
- Pussing2%
- Hair loss2%
- Dermatitis2%
- Increased hair growth2%
- Red skin rash2%
- Eye abnormality2%
- Abnormal vision2%
- Leukopenia2%
Risks and risk factors
- Severe skin reactions
- Asian ancestry
- Serious liver damage
- First 2 months of taking Dilantin (phenytoin)
- Changes in blood cell counts
- Suicidal thoughts or behavior
- History of depression
- Withdrawal seizures
- Stopping Dilantin (phenytoin) suddenly
- Suicidal thoughts or behavior
- History of depression
- Fever and inability to sweat
- Children
- Mental and cognitive changes
- History of metabolic disorders
- People also taking Depakote
- Kidney stones
- Low-carb diet
- Dehydration
- Drug interactions
- Vision problems
- Withdrawal seizures
- Stopping Topamax (topiramate) suddenly